A shipment of plutonium is stolen, leading Tony to be accused of smuggling nuclear materials into Japan and having to give a statement before the Diet of Japan. In order to get away from the press, Tony hitches a ride with a reporter he had previously met, Nanami Å?ta. While investigating the ship where the plutonium was being transported, Iron Man encounters another Zodiac warrior, Cancer.
Tony locates the culprits and drives them towards a security checkpoint, but he is blocked off by a self-proclaimed good Samaritan named Nagato Sakurai. Nanami mixes her camera with the plutonium the culprits were carrying and is chased by an armored tank equipped with stealth camouflage. After Sakurai helps Iron Man deal with the tank, Iron Man faces off against Cancer again and defeats him. Tony’s name is cleared and Nanami was able to write a good article.
Hurricanes rise for two scientists, and Stark uncovers a project involving weather control.
Stark plans a racing event to repair his company's image, which lures an assassin and a fellow hero.
Stark probes an epidemic that broke out near the Arc Station.
Stark finds a computer virus in the Arc Station, which threatens the city's systems.
Stark and Chika wake up to find they are stranded on an island, where Stark must find a way to survive without his arc reactor.
Iron Man vows to protect a girl with strange powers from Zodiac.
Yinsen steals plutonium to complete his Dio armor, spurring Stark into action.
Stark faces Dio without his Iron Man armor.
Stark gets arrested by the Japanese government, and explosions rock the parliament building.
Stark must become Iron Man again to stop Zodiac.