Joey arrives in L.A. after his new agent offers him his choice of parts on two TV shows, and befriends his neighbor, Alex . His nephew, Michael, wants to move in with him at his new apartment, but Joey fears that this will upset his sister, Gina.
Gina is having trouble letting Michael live his own life, and Joey and Gina try to teach him how to pick up women. Joey is irritated by the notes his super leaves him.
Having trouble meeting people in L.A., Joey throws a party to get to know some of his neighbors. The one he'd like to get to know, Jake, is more interested in Gina. Alex pretends to be Michael's girlfriend so that he can one-up his friend.
Joey joins Michael's book club to meet pretty women. Michael is crazy about a girl in the book club, who's only interested in Joey. Looking to get her work noticed, Gina bargains with Alex.
There's a vacant apartment in the complex, and Joey and Michael try to hide it from Gina, fearing that she'll want to move in to be closer to them. Also, Joey is understudying in three plays at once.
Michael is sick and Gina is delighted. Staying at Gina's, Joey meets her secret boyfriend. Meanwhile, an actor named Brian Michael David Scott repeatedly tricks Joey into missing auditions.
Joey donates his savings to Gina's plan to open her own salon, but she has second thoughts. Alex's husband returns to town, and Joey is mystified that Eric isn't threatened by him.
Gina's high school friend Donna comes to town, separated from her husband. Joey had a huge crush on Donna for years, and is happier than ever when they start going out. However, Donna confides in Gina that her husband wants to reconcile, and begs her not to tell Joey. Meanwhile, Michael is startled to discover that he was a great baseball player when he was younger.
Donna begged her not to, but Gina tells Joey about Donna's husband desire to reconcile. Joey takes Donna to a romantic bed-and-breakfast, but when Ron shows up in town, Donna ultimately ends up heading back to New York with him. Meanwhile, Alex discovers that she's hot and that hot girls get free stuff.
A discouraged Joey is just looking for an audition for a good show. At Alex's Northwestern alumni party, he's mistaken for an fellow alumni, and introduced to the Northwestern Mafia. They help him get an audition for a show called Deep Powder, described as "Baywatch on skis." Joey's a little depressed that he's auditioning for the father of two teenage characters.
Bobbie gets Joey a job as a celebrity judge for the Miss Southwestern U.S.A. pageant, taking place in Las Vegas. With Gina, Michael and Alex in tow, he heads for Vegas. While there, Alex reveals her Celine Dion obsession, Michael teaches Gina how to count cards, and Joey accidentally sleeps with a pageant contestant.
Joey meets Deep Powder's executive producer, Lauren Beck. Joey worries that he may be fired after giving away a plot twist at a press conference. Alex, Gina and Michael decorate the apartment for Joey for Christmas.
Joey's relationship with costar Katie has consequences that could get him fired from the show, unless he manages to talk her out of her dressing room. Joey and Lauren acknowledge their feelings for one another. After Gina teaches Alex how to make lasagna, Joey is forced to judge a taste test.
Unable to decide who to take to the premiere of Deep Powder, Joey struggles to find tickets for Gina, Michael and Alex. At the premiere, Michael meets both a girl and Brent Spiner and must choose who to leave with. Gina's date is Lauren's ex-boyfriend, Alex's date is a lesbian, and Joey and Lauren kiss.
Following Bobbie's advice to get an assistant, Joey winds up with Glen, who couldn't be better. But when Glen starts dating Gina, his worlds colliding means problems for Joey. Eventually, Gina and Joey create some guidelines so that Glen can continue working for both of them. Meanwhile, Alex mediates Michael's dispute over a patent with his friend Seth.
Bobbie has booked Joey on The Tonight Show with Jay Leno. En route to the show, he's stuck in a major traffic jam. After giving the finger to a guy who cut him off, Michael is terrified when they are stuck next to the guy's car. Gina meets two guys, one in an El Camino and one in a Mercedes. Alex saves the day when she shows up with a motorcycle that gets Joey onstage and hugging Jay Leno just in time.
Joey accidentally makes a date with a reporter from "People" for Valentine's Day. He has the gang "accidentally" bump into him and his date at the restaurant to ruin the mood, but his plans backfire when she thinks he's taking their relationship to the next level. A drunken Alex shares some sexual secrets with Gina. After Joey sends Michael over to hit on a table of girls, Michael actually becomes "one of the girls."
Joey is nominated for a Daytime Soap Award for his death scene on Days of Our Lives. (For the record, he was stabbed.) He is also presenting the award for Best Supporting Actress, and a problem arises when his inability to correctly pronounce one of the nominees' names leads to his saying the wrong name entirely. Meanwhile, Gina struggles with the fact that she is dressed unlike herself for the event.
Joey and Gina's sister Mary Theresa is coming for a visit, and Gina can't stand her because she thinks the world revolves around her. When Mary Theresa discovers that her engagement ring is fake, she decides to call off the wedding and stay in California, leaving Joey and Gina to try to find a way to get her to return to New York. Meanwhile, Michael is oblivious of a girl's interest in him.
When he investigates the hot women coming out of the apartment across the courtyard, Joey discovers beautiful new neighbor Sara, a photographer. She is surprisingly straightforward and asks Joey out. After his date with Sara goes well, Joey forgets to cancel his backup and she shows up at the complex. Sara lets Joey know that she'll be okay with him dating other women, but that she'll be seeing other men as well. Meanwhile, Eric is home for the first time in two months, and he and Alex are not getting along. They have a long talk and decide to separate.
As Eric moves out of their apartment and into one across the courtyard, Alex plants herself up in Joey's room with a pair of binoculars as Eric invites another woman over. After Alex goes to bed, Joey sees Eric kissing the other woman. Meanwhile, Joey's got problems of his own: even though he and Sara are allowed to see other people, he's not because he's too crazy about Sara. Trying to make her jealous, Joey discovers that she likes him as much as he likes her, and they decide not to see other people.
Just as Joey and Sara become exclusive, Joey has to do a love scene with Carmen Electra for Deep Powder. Meanwhile, Alex struggles the knowledge that Eric kissed another woman.
Joey asks Bobbie to help Sara find work. Sara gets a job working for Newsweek in Washington DC. Trying to get her to stay, Joey tells Sara he loves her and asks her to move in. Meanwhile, Michael's new girlfriend, a 45-year-old woman, cheats on him with a 60-something professor. Alex is struggling to keep herself together.
After asking Sara to move in with him, Joey freaks out. Sara freaks out too, and leaves without saying goodbye. Joey is heartbroken. On her first date in a long time, Alex accidentally offers sex to the guy, and Joey gets rid of him. While doing shots in Joey's bedroom and commiserating about the sad state of their love lives, Alex and Joey kiss! Meanwhile, Bobbie sets herself up with Michael at a Star Wars preview. When Gina confronts Bobbie about being attracted to Michael, Bobbie offers her a job.
On the set of "Blue Powder," Joey's character is still unknown. One of the show's extras, Zach, offers Joey some advice on how to make it as an actor in Hollywood. Meanwhile, Jeanne, a young actress moves into the apartment building and is looking for Joey; so Michael pretends to be Joey in order to get a date with the actress.
Joey begs for one more chance, so he re-reads his lines to a bunch of producers. However, the producers want to hear lines spoken by kids because they're holding auditions for a different movie.
Joey has to put up with an annoying child actor on the set of his new movie, so Joey decides that he needs to take a stand and he spanks the young actor. Meanwhile, Gina tries to comfort Alex, who has a lagging love life.
Joey is preparing to shoot a big fight scene on the set. The director offers to use a stuntman instead but Joey wants to do his own stunts. Eventually, Chuck, Joey's stuntman, comes in. Abby, the script supervisor, has a chat with Joey because he doesn't follow the script at all. Michael visits the set and he and Abby hit it off. Zach works Craft and Services on the set. Meanwhile, Alex is confused about her true feelings for Joey.
Joey decides to buy a house now that he is bringing big bucks from the movie but can he convince the owner of the house that he should get it? Gina isn't very supportive of the idea. Alex helps Bobbie with a harassment case.
Joey decides to enroll in an English as a second language class just to attract the attention of a beautiful woman. Elsewhere, Gina decides to help Bobbie try and find a new client.
In an effort to keep Joey away from his attractive new interior designer, Alex tries to teach him Texas Hold 'em. But when Joey gets frustrated with losing, she begins to get creative with the rules of the game -- which make things very interesting when Joey is asked to go on Celebrity Poker Showdown.
An old girlfriend of Joey's is still mad at him for something he did to her years ago. She sends him a tape from his past with embarrassing footage and threatens to go public. To appease her, he agrees to apologize on The Ellen DeGeneres Show.
In order to impress his new girlfriend, Joey agrees to direct her grandmother's musical at the Senior Citizen Home. He must turn to his best friend Zach to help him after everyone realizes that he's not a gifted director.
It's Thanksgiving at Joey's! Joey and Zach run into trouble when they discover ancient Native American artifacts on Joey's property and mistakenly give them away. Meanwhile, Gina is trying to have a meaningful family Thanksgiving with Alex and Michael but Joey isn't cooperating with her plans.
Joey's best friend from high school, Jimmy, comes to visit Joey after years of not having contact. He reveals a major surprise to Michael and Gina which throws their world out of balance.
After Michael breaks up with his girlfriend, Joey and Zach take him to Tijuana to help him get over it. After a rowdy night, Joey and Zach find themselves in an awkward situation which brings them a little too close for comfort.
Joey throws a holiday party in his old apartment and has to iron out some bumps with Alex. Meanwhile, Bobbie attends the party with her controlling boyfriend who does not deal well with the situation.
Joey begins acting weird with Alex when she sets off on another romance with Dean. Meanwhile, Joey's action figure arrives with some quality control issues.
Joey is flummoxed by the fact that Carmen Electra has a bigger billboard on Sunset Blvd. Also, Joey must deal with the fact that he and his father don't have the same interests on the night of his first big premiere.
When Joey hears that Dean is planning Alex a birthday party at which he also plans to propose, Joey decides that he wants to confess his feelings for her. Meanwhile Michael wants to be the DJ for the party, and Jimmy and Gina get tattoos to show their feelings for each other.
When Joey tries to move into his new house, he finds the house is on fire. Jimmy finally learns that Michael is his son and tries to build a relationship with him.
Bobbie sets Joey up on a date with Edie Phillips, but what Joey doesn't realize is that she only needs him as a "beard" to hide her homosexuality from the press.
Joey employs Jimmy as his Development Coordinator at his new production company "Yes, I am a Bird". He also realizes that a girl has set up a website criticizing his acting talents.
Joey and Alex realize that they both have feelings for each other but while Joey wants to act on those feelings, Alex doesn't because she feels they will hurt each other. To try to get Alex to go out with him, Joey invites her to be in the audience when he is a guest on Inside the Actor's Studio. Meanwhile Jimmy wants to buy an engagement ring but needs a way to get money.
In order for Gina to marry Jimmy, he needs to divorce his wife, who he married when she was in prison for her money.
When they visit her at prison, she gives Joey tips on how to improve his relationship with Alex.
Gina and Jimmy plan to get married, with Alex planning the wedding, which leads Joey to believe that Alex wants to get married again. But they both get cold feet and run off to the bus station where they meet each other. Meanwhile Joey has been picked to pitch the starting ball at a baseball game, and is desperate to get it right.