Dr. Thomas Burke, an expert in behavioral psychology, is putting his talents to use by brainwashing men into becoming zombie-like assassins for the benefit of Syndicate executive Alex Pierson. The IMF must convince Pierson that Burke is sending a programmed assassin after him, and Barney must become the next zombie-killer. However, when he loses the pill that protects him from Burke's brainwashing, he becomes a killer for real.