Kate puts the nurses in quarantine after a suspected anthrax outbreak - but all is not as it seems. Beth thinks Justyn tricked her into sleeping with him and plots revenge. Anji attends her school reunion, and meets the teacher she used to have a crush on, while new couple Jamie and Lia are appalled by their own soppiness.
Beth begins to feel lonely without her best friend Anji and leaves St Margaret's for a new job at a private hospital, where she soon becomes the centre of attention. Kate's eagerness gets the better of her on the nurse practitioners' course, and Dr Callum grows jealous of Justyn's popularity with the patients. Lia launches a personal crusade after her car is clamped, with unexpected results.
A job offer from overseas puts Jamie and Lia's relationship to the test, while Kate tries to defend an increasingly unstable Dr McManus from a new registrar and army doctor. Callum, Beth and Justyn agree to undertake a clinical trial for a mystery drug - but only two of them experience adverse effects.
A pregnant Anji returns home from her travels, and goes to devious lengths to ensure she won't have to raise the child alone - finding unexpected help from Callum. Beth takes an unusual form of revenge on the girlfriend of a good-looking patient, and Kate is left feeling guilty when she stands up to Peter.
Kate is puzzled when Peter makes an offhand comment that may have been his version of a marriage proposal, but she is left unsure over his intent. Beth is cajoled into going camping with one of the hospital plumbers and gets more than out of the trip than she expected.
Kate becomes excited about the prospect of getting married and talks constantly about dresses and flowers - much to the bemusement of fiance Peter. Lia dates a younger man, and gives a lecture on sex education at her daughter's school. Beth decides to give hospital plumber Rob a second chance, and Anji faces a dilemma when choosing her birthing partner.
Kate prepares for her wedding to Peter by taking him to visit her dream home, but is upset by his lack of interest, and matters only get worse when she discovers he has applied for a job abroad without telling her. Proud mum Anji tries to make up with Callum, Beth and Rob's relationship goes from strength to strength, and Emma convinces Lia to take a trip to Australia.