Antwon Tanner (Skills) does not appear in this episode.

Ratings: 3.25 million viewers

We learn that Haley is the one that's pregnant.

othpodcast.com features a full-length commentary on this episode with series creator Mark Schwahn as well as writer Terrence Coli.

Hip-hop star Lupe Fiasco performs live at TRIC.

The bathroom used for the scene where Rachel is getting ready for her test shoot was build solely for that scene.

The Maxim magazine photo shoot that we see Rachel take part in in this episode is an actual shoot. The October 14th, 2006 addition of Maxim featured One Tree Hill stars Danneel Harris, Hilarie Burton and Sophia Bush.

Lucas: (voiceover) There comes a time when every life goes off course. In this desperate moment who will you be? Will you let down your defenses and find solace in someone unexpected? Will you reach out? Will you face your greatest fears bravely or move forward with faith? Or will you succumb to the darkness in your soul?

Lucas: (voiceover) There comes a time when every life goes off course. In this desperate moment you must choose your direction. Will you fight to stay on the path while others tell you who you are? Or will you label yourself? Will you be honored by your choice? Or will you embrace your new path? Each morning you choose to move forward or to simply give up.

Brooke: Burn me at the stake, but I like boys and I like sex.
Shelly: So did I, but --
Brooke: So did I? Wait a minute? You have a virginity club, and you're not even a virgin?
Shelly: I am now. I'm a born again virgin.
Brooke: A what?
Shelly: Just because you make a mistake, doesn't mean you can't start over. I made a pledge, I'm recommitted.
Brooke: Shelly, I hate to break it to you, but your either a virgin or your not. And a pledge does not a broken hymen mend.

Haley: Nathan bought a motorcycle.
Brooke: Well, Rachel (whispering) thinks I should have an abortion.
Haley: Okay, your's is worse.

Mouth: Tough night, huh?
Brooke: Stupid rumors.
Mouth: Brooke, um, the other night at the party, you and Rachel thought I was asleep, but I wasn't. I heard you talking and I know Rachel thinks you shouldn't have this baby, but she's wrong. You are gonna make a great mother. I honestly believe that.
Brooke: I need to tell you something.

Haley: Nathan? God, what happened?
Nathan: It's okay, don't worry. These days can, I don't know, they can graft skin from my ass.
Haley: Are you hurt anywhere else?
Nathan: No, I'm fine. The bike's pretty messed up though.
Haley: Bike. Great. Okay, I want you to get the car back as soon as you can because I need you on this planet.

Karen: Deb fired me.
Dan: Fire is her specialty.

Haley: Stay away from him! For all I care you can go to hell, but I won't let you take Nathan with you.
Deb: Talk to me in a few years Haley, when your dreams are dead and your child betrays you. Then we'll see what kind of mother you'll be.
Haley: No, no, I will never, ever be like you Deb.
Deb: Pretty soon Nathan's going to realize playing college basketball is a lot more fun than playing house. I'll save you some pills.
Haley: Who are you kidding Deb? Junkies don't save pills.

Haley: Nathan, I know that it's really hard for you to explain what happened to you down under that water and maybe Keith did save you, maybe you saved yourself. I don't know, but the point is either way it means that you are supposed to be here right now.
Nathan: Hales, that's not it. My mom came into school today and in front of everybody chose pills over me.

Episode Title: Can't Stop This Thing We've Started

"Can't Stop This Thing We've Started" is the title of a song by Bryan Adams.

Haley: Hidey-ho, neighbors.

In The Simpsons, Ned Flanders often greets the Simpsons with "hidey-ho, neighbors".

Lucas: So how was the Manson family reunion?

The Mason Family was the name given to the group led by convict Charles Manson. The group was responsible for the 1969 Tate-LaBianca murders.

Haley was wearing the maternity shirt that Brooke was making in "Things I Forgot at Birth".

Karen: Deb fired me.
Dan: Fire is her specialty.

In "The Show Must Go On", Deb reveals to Dan that she tried to kill him in the dealership fire, not Keith.