|Except for the "Pilot", each of the episodes are named after songs or albums. For the episodes that are named after songs, the plot of the episode typically relates to the lyrics in some way.|
|Production of the series began on August 12, 2003, approximately one month before the series premiered.|
|The working title for the series was Ravens, named after the mascot of the Tree Hill High team.|
|One Tree Hill films in Wilmington, North Carolina.|
|In the original version of the pilot, Lucas' best friend was named Reagan instead of Haley and played by Samantha Shelton, not Bethany Joy Lenz. After One Tree Hill was picked up by the WB and added to the fall schedule, the character was renamed to Haley James and was re-casted.|
|Episodes that do not feature the opening credits and theme song and feature the One Tree Hill logo instead are typically episodes that have a serious, more dramatic storyline such as the school shooting episode, "With Tired Eyes, Tired Minds, Tired Souls, We Slept".|
|Stars Chad Michael Murray (Lucas Scott) and Sophia Bush (Brooke Davis) met on the set of the series, dated, and married on April 16, 2005. They announced their separation on September 26, 2005 and subsequently filed for divorce. Their divorce was finalized in December of 2006.|
|Though James Lafferty's character (Nathan) has his nipple pierced, Lafferty does not. For each scene where Nathan is shirtless, a nipple ring has to be glued on.|
|James Lafferty is the only cast member that was actually a high school aged teenager when filming of the series began. Every other cast member was older than 20.|
|The baby who plays Jenny, Jake's daughter, is actually 4 different babies: three girls and one boy. Two of the girls are twins named Erin and Emily.|
|Artist Helen Ward draws all of Peyton's artwork used in the series.|
|One Tree Hill Musical Guests:|
- Gavin DeGraw: "You Gotta Go There to Come Back" and "What Comes After the Blues"
- Sheryl Crow: "The First Cut is the Deepest"
- The Wreckers: "The Hero Dies In This One"
- Jimmy Eat World: "The Tide That Left and Never Came Back (1)"
- Fall Out Boy: "An Attempt to Tip The Scales" and "Just Watch The Fireworks"
- Nada Surf: "Return of the Future"
- Jack's Mannequin: "Just Watch The Fireworks"
- Michelle Featherstone: "The Show Must Go On"
- Lupe Fiasco: "Can't Stop This Thing We've Started"
- Within Reason: "You Call It Madness, But I Call It Love"
- The Honorary Title: "In Da Club"
- Kate Voegele: Recurring throughout season 5 (firs