The female head of a homicide squad leads her team in solving homicides while juggling her personal life.
Jane's father's bar is robbed while she's helping out at the establishment; Calderon and Jane are assigned to the murder of a woman found in a Dumpster. In other events, Jane gives the female cop (Elizabeth Rodriguez) investigating the bar robbery the cold shoulder.
When a good-looking stockbroker is killed mysteriously, Jane automatically suspects his wife. Meanwhile, Jane enlists the help of a hypnotist to fight her addiction to smoking. Elsewhere, Matt is furious when his ex-wife suggests Jane shouldn't attend their son's birthday party.
Jane and Duffy are on the case of a middle-aged man found robbed and dead in a hotel. After watching surveillance tapes Jane searches for a wig-changing prostitute. Meanwhile, Duffy manages to get under Jane's skin after making comments about her relationship with Costello.
The death of a boy at a pre-school is investigated.
Jane and Reg are taken out of the city when parents of a young girl are found murdered in a hotel room. Jane has a hard time convincing the young girl to speak with her about the man that killed her parents. Meanwhile, Reg and Jane find themselves in harms way.
When a 5-year-old kid is found dead at school, the investigation gets personal for Jane.
When a Jewish diamond dealer is found dead, Jane looks for answers from his wife. Blando and Jane investigate some rappers in Brooklyn after getting a strong lead. Meanwhile, Matt gets a huge job and surprises Jane with a celebration.
Jane and Evrard go to Chinatown to investigate a murder during a game of mahjong. Jane and Evrard can't seem to get a break on the case when a big shot lawyer seems to make all the witnesses disappear. Meanwhile, Reg lets Matt in on a little secret about Jane.
Duffy and Calderon have the unpleasant task of telling a grandmother that her young granddaughter was raped and murdered. Jane and Augie are on the ritzy Upper East Side when a woman is found mysteriously shot during the night. Meanwhile, Jane has a heart to heart with Matt.