David and Jill make a trip to Colorado where a rampant SARS-like outbreak is occuring. David is in shock when he discovers that the outbreak is Spanish Flu, a virus not seen since 1918, except when David dug it up in Nunavit. Racked with guilt, he inadvertantly walks into the path of a car and is sent to the hospital in a coma.

Mayko heads to Colorado to try to find Patient Zero in the Denver outbreak.