Stoopid Monkey, the production company created by Seth Green and Matthew Senreich, has a different logo at the end of each episode featuring the stupid monkey in various forms of danger.
This episode introduces the recurring character
The Bloopers Host
The head used to describe Corky from the ABC show Life Goes On is actually the head of the Disney character Quasimodo from The Hunchback of Notre Dame.
Former President George W. Bush is wearing an Air Force flight suit similar to what he wore aboard the USS Abraham Lincoln during the infamous Mission Accompished debacle.
"This is your brain Segment" - This segment is a parody of Rachael Leigh Cook's famous Partnership for a Drug Free America Public Service Announcement.
Teletubbies is a British children's television program.
"Optimus Prime Gets Cancer Segment" - This segment is a parody of the tv show, Transformers.
The sketch features the characters ...
Bumblebee & the Dinobot, Grimlock
The Dinobot, Swoop
Prowl (left of Prime)
In a parody of the HBO prison series, OZ
... The Wizard of Oz character Scarecrow gets stabbed by a fellow inmate as the other characters, the Tin Man & the Cowardly Lion look on.
The Marvel character, The Human Torch is featured in a sketch complaining about medical issues.
During the Bloopers segment, The 1970's show, The Dukes of Hazzard (1979-1985) is featured w/ the characters Bo Duke & Luke Duke
During the Bloopers sketch, various replacements are seen for FOX's X-Files show.
These are ...
Neo from The Matrix series of movies.
And who is supposed to be Corky from the ABC show, Life Goes On (See episode goofs)
The Adventures of Superman (1952-1958) starring George Reeves, is featured in the Bloopers segment.
The characters from the 80s sitcom Diff'rent Strokes (1978-1985) are seen in the Bloopers segment.
(l to r) Arnold Jackson played by Gary Coleman, Kimberly Drummond played by Dana Plato, Willis Jackson played by Todd Bridges & Phillip Drummond played by Conrad Bain
Two Pokemon characters are shown in a quick skit.
Pikachu & Squirtle
Characters from the classic Star Trek series are featured in the Bloopers segment.
Captain James T. Kirk
Spock (blue), Montgomery Scott (Red) & Hikiru Sulu (yellow), although he appears to be Dr. Leonard McCoy.
During the Bloopers sketch, characters from Battlestar Galactica (1978) are seen.
(l to r) Lieutenant Starbuck played by Dirk Benedict, Commander Adama played by Lorne Greene and the robotic nemesis of the series, a Cylon