Actor Luke Wilson hosts. Musical guest U2 perform tracks from their latest album.

Sketches:"White House Apprentice", "Debbie Downer", "American Trainwreck Awards", "TV Funhouse: George W. Bush's Homocranial Machine", "Feeding Buddies", "Coolest Teacher At Benton Township High School", "The Falconer", and "Drunk Businessmen."

Performances:U2 performs: "Vertigo", "Sometimes You Can't Make It On Your Own", and "I Will Follow"