Actor John Malkovich hosts; T.I. performs "Whatever You Like" and "Swing Ya Rag" (feat. Swizz Beatz).

Sketches include "A Message from Secretary of State-Designate Hillary Clinton," "Gas Rite Commercial," "Shana, The New Girl," "Barack Obama Keeps It Cool," "La Rivista Della Televisione Con Vinny Vedecci," "Virgania Horsen's Pony Express," "Calculator for Christmas," "Weekend Update" with guests Plaxico Burress, Boy George, and nine-year-old author David Rasmusen, "The Lost Works of Judy Blume," "Digital Short: Jizz in My Pants," and "J'acuzzi."