Clark returns to Smallville re-programmed as Kal-El. Intent on fulfilling his destiny, Kal-El takes to the skies to steal a powerful kryptonite crystal. Determined to save her son, Martha turns to Dr. Swann's emissary, Bridgette Crosby, and learns about a surprising new form of kryptonite. Meanwhile, Lois Lane comes to town to investigate the murder of her cousin Chloe. Also, Lana returns from Paris with a new attitude and a new boyfriend, Jonathan lies in a coma, and Lionel faces a grim new life in prison...
Songs: Tahiti 80 -- Better Days Will Come, San Drine -- Plus Pres De Moi
Clark faces a surprising new foe in the form of a shy high school girl who turns to plastic surgery to enhance her looks and boost her popularity. However, things go awry when she discovers that her kryptonite-enhanced beauty causes harm to anyone she kisses - and she decides her next victim will be Lana. Meanwhile, Jason and Lana continue to hide their relationship from Clark.
Clark joins the football team at school and is immediately given the starting quarterback position after the old quarterback starts a fight with new coach Jason. Curious about the behavior change in his old teammate, Clark and Lois investigate and discover that the cheerleaders are poisoning the teams' water with kryptonite, turning the players into Stepford-like boyfriends...
Songs: Hawk Nelson
-- California, Silver -- Cruek Sun, Ash
-- Meltdown, Sam Roberts
-- On The Run, Authority Zero -- Revolution
Songs: Jimmy Eat World. -- Pain
Chloe is drawn into an underground gambling ring at school run by foreign exchange student Mikhail Mxyzptlk and loses her savings on a football game after Mxyzptlk uses his powers to control all the players -- including Clark. When Chloe discovers Mxyzptlk's secret, he kidnaps her and threatens to kill her unless Clark throws the championship game. Meanwhile, Lex threatens Mxyzptlk with deportation unless he uses his powers for Lex's benefit.
Songs: Green Day
-- Boulevard Of Broken Dreams, Shiloh, -- I Believe, Bosshouse
-- I'm All Gone, Social Distortion -- Reach For The Sky, The Hives
-- Walk Idiot Walk
After Lana reads from a spell book written in the 1600s, she, Lois and Chloe become possessed by witches that had been burned at the stake. The three witches have come back seek revenge and search for the powerful Kryptonian crystals, wreaking havoc on the town in the process. Clark attempts to stop the witches but they strip him of his powers and force him to reveal the location of the crystal he hid in the cave before the meeting.
Black Toast Music -- Blame, Shubert -- Impromptu No. 2 In E Flat, Keane
-- We Might As Well Be Strangers, Gwen Stefani
-- What You Waiting For
Amanda O'Connor -- Daddy's Little Girl, Faithless
-- Want More: Part 2
Lex's secret experiment at Luthorcorp goes awry and causes a dangerous toxin to be released into Smallville. Those infected by the toxin, including Clark, Lana, Lex, and Jason imagine their greatest fears come true and then fall into a coma. Desperate to find a cure, Clark gives some of his blood to Lex and is stunned at what Lex does with the antidote.
Claiming to be cured, Alicia is released from Belle Reve hospital and comes to Smallville to rekindle her relationship with Clark. Initially skeptical of Alicia, Clark finds himself enjoying a relationship with someone who knows his secret, but when she pushes for more he hesitiates, causing her to use red kryptonite on him. "Bad Clark" emerges and whisks Alicia off to get married in Las Vegas. Meanwhile, Lana decides to have sex with Jason in order to win him back...
Johnathon Rice -- Break So Easy, Rock-N-Roll Soldiers -- Funny Little Feeling, Simple Plan
-- Welcome to My Life
Lana and Jason are attacked and almost killed by an unseen assailant and Alicia seems to be the prime suspect. Clark initially defends his new girlfriend, but when the evidence begins to pile up he is forced to take a hard truthful look at Alicia. Hurt by Clark's actions, Alicia forces Clark to unknowingly reveal his powers in front of Chloe. Meanwhile, Jason's mother returns to town with an offer for Lex...
While driving, Lois accidentally hits a dog and brings it back to the farm to heal. Clark realizes this is no ordinary dog after the pup lifts up a car to retrieve a ball. Clark and Lois learn the dog is a product of an aborted LuthorCorp experiment and is being used to commit crimes, but when Lois is kidnapped by the robbers and Clark is weakened by kryptonite, it is up to the dog to save them. Meanwhile, Lana questions Jason's involvement in his mother's schemes...
Songs: Supertramp -- Give a Little Bit
Songs: Ashlee Simpson -- La La
Clark must stop the school photographer after he sets up a secret simulated high school and begins kidnapping students -- starting with Chloe -- to keep the glory days of high school going forever. Lex and Lionel are kidnapped and tortured by the Teagues in an effort to find the crystal. However, after Genevieve realizes Lana has the crystal, she decides to put an end to the hunt once and for all...