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The life of Eric Cartman will never be the same after going in for a routine tonsillectomy. A mishap at the hospital results in Cartman being diagnosed with an incurable disease, and with little support from his friends. Now he is determined to find a cure, even if it costs him all his toys.
Cartman: I'm not just sure.. I'm HIV positive.
Waitress: I'm afraid AIDS benefits aren't as popular as they use to be. AIDS is more the 80s/90s disease. It's all about cancer now.
Cartman: Well that's just great! Of all the times to get AIDS, I get it right when everyone stops giving a crap.
Cartman: All right, now get the rope up over that third rafter above the window. That's the easiest access.
Butters: Wow.. you really know what you're doing.
Cartman: Yeah, I sneak in to Kyle's room lots of times.
Cartman: We have to see Magic Johnson right away. You see.. we have AIDS.
Airport Employee: AIDS? Wow, that's really.. retro.
The subject of AIDS was also the main focus of the season 6 opening episode "Jared Has Aides
," very similar to "Tonsil Trouble" being the season 12 opener.
Rosie O'Donnell picture
In Principal Victoria's office there is a photo framed of her next to Rosie O'Donnell. This is a reference to the episode "Trapper Keeper
" when Rosie came to South Park elementary school.
As Kyle is breaking toys in Cartman's room you can see a toy figure of Lambtron, which appeared in the episode "Chinpokomon