After a Thracian warrior rebels against a former Roman ally, he and his wife are captured and sold as slaves.
Her fate is uncertain, but his punishment is to die in battle in the gladiatorial arena.
Following his surprising survival at the games, the newly christened Spartacus arrives at the ludus of Batiatus, where his new master promises to reunite him with his wife Sura, as long as he trains as a gladiator.
Spartacus has now proved himself during training and wears the attire of a gladiator, but his coarse attitude and relentless quest to see his wife, isolates him from his fellow gladiators and trainer Doctore.
Having failed shamefully in the arena against Crixus, Spartacus is forced to fight in the underground Pits. Batiatus is determined to profit from Spartacus, and may be at risk if his debts aren't repaid.
Spartacus and Crixus are teamed up in order to take on an unbeaten champion in the arena. Elsewhere, a financially broke Batiatus receives an opportunity of a lifetime that involved his band of battling gladiators.
Barca hopes to buy his and his male lover's way out of slavery.
Spartacus anticipates his promised reunion with his enslaved wife, as reward for a monumental victory in the arena, while still working on an escape plan.
Overcome by the pressure of being under Batiatus's control, Spartacus must make a choice: whether teave his past behind and assume the mantle of a champion gladiator, or die, trying to be free.
After Batiatus purchases a new batch of slaves during an auction to be trained as gladiators, he ponders the idea of selling Crixus.
Batiatus informs Spartacus that he is to sexually service one of the richest woman in Rome.
Spartacus and Crixus are selected to fight each other in an exhibition match for Numerius' birthday - but Crixus is intent on spilling Roman blood instead.
While Spartacus hovers dangerously on the brink, Batiatus plots revenge against his many enemies.
Lucretia and Batiatus anxiously await the arrival of Glaber.
Spartacus has come up with a plan for revenge.
Spartacus convinces Crixus and the other gladiators that they could easily overpower the ludus guards and gain their freedom, and vows to kill Batiatus, as revenge for his wife's death.
Spartacus discovers just how grave the responsibilities and costs involved in his new role as a leader of freed slaves are. Claudius Glaber’s arrival in the city of Capua forces Spartacus to keep his rebellious band together.
Spartacus and his rebel band liberate a Roman villa, but its slaves are wary of them. Oenomaus throws himself into the brutal fighting Pits, and Glaber supports Lucretia’s prophecies, despite Ilithyia’s protests.
After learning of Naevia's fate, a rift forms among the gladiators; Lucretia divulges a long-kept secret in order to strengthen her position; and the rebels find themselves at risk after an attack.
Spartacus leads the survivors through the woods, but Crixus gets separated and captured and returns to a place of past suffering. Lucretia pries into Ilithyia’s affairs, while also seeking influence with a powerful Roman.
Spartacus leads a daring mission to free Crixus from Roman captivity, but a former gladiator from the House of Batiatus complicates matters. Ilithyia’s scheming has possibly put her marriage to Glaber at risk.
While Glaber welcomes some powerful new recruits to his forces, Spartacus rallies the rebels to start training in order to be ready to defend their new sanctuary from the Romans.
Spartacus looks to increase the size of the rebel force by freeing and recruiting fighters held as slaves during foreign wars; Lucretia recruits one of her husband's ex-gladiators in an attempt to outmaneuver some influential Romans.
Spartacus seeks an opportunity for exacting revenge after the capture of an influential Roman. Intrigue is at a high level among Glaber and the women in his circle.
Spartacus has to try and convince his people to unite against the imminent Roman assault. Lucretia struggles to be free from the orders of men who threaten her destiny, and Glaber discovers that his ruthlessness has consequences.
When dwindling supplies threaten to bring the rebellion to its knees, Spartacus tries to restore hope among his people.
Spartacus continues to assemble a formidable rebel army and to outwit the best of Romes commanders. The powers of the Empire are desperately forced to turn to wealthy, ambitious Marcus Crassus for his help with the campaign.
Spartacus attempts to launch a bold assault to obtain food and shelter for his followers, while Crassus raises a formidable army and welcomes the arrival of a surprise visitor.
Spartacus strikes a deal with a band of travelling marauders to ensure his people stay supplied and fed. Crassus' son Tiberius makes a bold and fateful decision regarding his future.
The possible infiltration of a Roman spy into the rebel camp, causes tension to mount between Spartacus and his men. Crassus resurrects a long abandoned form of Roman punishment to teach his soldiers a brutal lesson following their cowardice in the recent battle.
Spartacus puts a plan in motion to weaken Crassus' forces and gain the upper hand on the battlefield,but a betrayal threatens to foil his plan.
When Crassus attacks the rebel-occupied city, Gannicus becomes trapped behind enemy lines. Meanwhile, Crassus orders his son Tiberius to arrange a celebration for a man he loathes.
With their forces trapped on an impassable, snowbound ridge, Spartacus and Crixus clash over a method of escape. Crassus findsit increasingly difficult to control the actions of those closest to him.
Spartacus and the group of rebels come to a crossroads in their quest for freedom, while a relentless Crassus doggedly drives his men in the pursuit of Spartacus and his forces, while the conflict between Tiberius and Caesar intensifies.
Crassus discovers another Roman is apparently trying to take credit for crushing the rebel forces, while Spartacus attempts to secure a bargaining chip to use against his conquerors.
Spartacus and his army of outnumbered rebels make one last attempt to win their freedom in a final battle against the advancing Romans led by Marcus Crassus.