Doctor Strange makes his first and only appearance in Spider-Man.
Doctor Strange has never appeared on television in any other occasion.
Baron Mordo and Dormammu make their first appearance, though they will later return in "Venom Returns (1)
This episode picks up where the second season finale left off.
We see for the first time what Mary Jane's father looks like in this episode, although he doesn't physically appear.
Mary Jane's father is shown twice in this series, both in which he's an illusion.