Everything is running normal on Voyager
when Janeway suddenly receives a coded message from the ship. It’s the highly secretive Omega Directive, which orders all Star Fleet Captains to stop everything, and do everything in order to destroy a detected Omega molecule.
Seven is the only member of the crew Janeway tells about this directive, in the hope that Seven can help her with this task, but Seven decides it might be better to study the highly unstable molecule. This leads to near disastrous results for Voyager