Dean: (about Sam) You got to figure out what the hell he is and fast.
Bobby Singer: I'm trying. But, Dean, there's a worst case scenario.
Dean: What, Satan's my co-pilot? Yeah, I know.
Bobby Singer: Well, that'd be the other worst case.
Dean: Well, then what?
Bobby Singer: Maybe it's just Sam.

Sam: There's another one.
Dean: Yeah, what?
Sam: Dentist drilled a guy to death.
Dean: You mean the non-sexy kind of drilling, right?

Dean: Castiel? Hello? Possible loose nuke down here, angelic weapon. Kinda your department. You hear that, Cass?

Castiel: It isn't the Horn of Truth.
Dean: What 're you talking about? You were gone for like two seconds. Where did you look?
Castiel: Everywhere.

Breast Woman: I'm sitting like this so you'll look at my breasts. I just bought them. I need a lot of attention.
Dean: Good luck with that. (walks away, comes back, smiles)

Dean: Hey, anything you're itching to tell me?
Bobby Singer: Not really. Sorry to disappoint.
Dean: Ah, that's all right. I'm just testing a theory.
Bobby Singer: Well, I'm here hitting the books while drinking a nice glass of milk and watching Tori and Dean.
Dean: Wha? Wait, who, who and Dean?
Bobby Singer: Tori Spelling. I'm a huge fan. Girl's a real talent.
Dean: I guess it does work over the phone.
Bobby Singer: You know what else? I get a pedicure once in a while. This nice Vietnamese joint...
Dean: Okay, okay, please stop
Bobby Singer: There's one gal, Nhung Phuong, name means "velvet phoenix." Tiny thing, but the grip on her. She starts on my toes, and I feel like I am going to...
Dean: Whoa, whoa, hey, come on. Now I"m scarred for life. Thank you.
Bobby Singer: I never told anyone that. Why am I telling you? Maybe because you're my favorite. Although Sam's the better hunter. Lately, anyway. Whoa! Why the hell am I telling you this?

Title:

A Few Good Men (1992) stars Tom Cruise as a JAG officer trying to find the truth about a death during Marine training. The line "You can't handle the truth" is spoken by Jack Nicholson's character.

Dean: And then big sister's taxicab confessions sends her over the edge.

Taxicab Confessions is a series on HBO where cab drivers with hidden cameras pick up passengers, then get them to talk about their personal lives.

Dean: What? Satan's my co-pilot?

Goid is My Co-Pilot is an autobiography of a World War II pilot, Robert Lee Scott Jr.

Dean: Anything from Marathon Man?

Marathon Man is a 1974 novel by William Goldman, made into a movie in 1976. It is best known for a scene where a Nazi war criminal tortures a man by drilling into a healthy tool without anesthetic, and asks him repeatedly, "Is it safe?"

Sam: Not just Dr. Giggles.

Dr. Giggles is the title character and killer in the 1992 slasher flick of the same name.

Dean: You've been Terminator since you got back.

Terminators are nigh-unstoppable robots wrapped in flesh, initially sent back from the future to alter the past and assure the victory of their computer overlords. The first one appeared in The Terminator (1984).

Dean: Soylent Green situation?

Soylent Green is a 1973 science fiction set in a near-future Earth where it is ultimately revealed that a popular foodstuff, Soylent Green, is made out of people.

Veritas: Mallory to your Mickey.

Mickey and Mallory are the homicidal couple in the 1994movie Natural Born Killers.