Edgar: Strange, isn't it, that someone would choose to be named "Dick"?

Castiel: Will you look at her? My caretaker. All of that thorny pain. So beautiful.
Meg: We’ve been over this. I don’t like poetry. Put up or shut up.

Castiel: Did you know that a cat's penis is sharply barbed along its shaft? I know for a fact that females were not consulted about that.

Castiel: This is the handwriting of Metatron.
Sam: Metatron?!? You’re saying a Transformer wrote that?
Dean: No, that’s Megatron.
Sam: What?
Dean: The Transformer, it’s Megatron.
Sam: What?

Castiel: Oh, Inias, Hester. I—I know you want something. Answers. I... I wish it could be that... There are still many things I can teach you. I can offer, uh, perspective. Here, pull my finger. Uh, uh, Meg will get another light and I’ll blow it out again, and this time it’ll be funny, and we’ll all look back and laugh.

Castiel: We were assigned to watch the Earth. Often it was boring. Your wars were very boring. Sex… repetition.

Dean: You’ve been chosen. And it sucks. Believe me. There’s no use asking “why me,” because the angels, they don’t care. I think maybe they just don’t have the equipment to care. It seems like when they try, it just... breaks them apart.

Sam: It says we need to start with the blood of a fallen angel.
Castiel: Well, you know me. Always happy to bleed for the Winchesters.

Dean: That's a lot of fuss over a caveman Lego.

Legos are small toy building blocks used to make millions of different objects, places, structures, animals, and people.

Meg: What up, Bullwinkle?

Bullwinkle is the overly tall talking moose from The Rocky and Bullwinkle Show.

Sam: You saying that a Transformer wrote that?

The Transformers are robots, often of giant size, capable of transforming into weapons and vehicles. They started as a toy line by Hasbro but were soon spun off into comic books, movies, and television shows.

Dean: We need the tablet to end Dick Roman’s Soylent Us crap.

The 1973 s.f. movie Soylent Green is set in a dystopian future of 2022 suffering from overpopulation and depletion of natural resources. The people are fed by what is supposedly a plankton derivative, Soylent Green, which turns out to be made out of people.