Sam: What is wrong with you?
Dean: What's wrong with me? You kidding me? This is a first edition, dude. Do you know what this would go for on Ebay?
Sam: Nope. Why, do you?
Dean: No. Maybe. Shut up.

Dean: Well, he puts the "ass" in "Cass," huh?

Sam: Wait a second. You've been telling Crowley the location of Lucifer's Crypts.
Meg: What can I say? I needed a break from the constant torture.

Sam: Wait--so... a bunch of innocent people died so you could buy yourself some time?
Meg: Hi, I'm Meg. I'm a demon.

Sam: Wait a second. Did you just say "angel tablet?"
Meg: You know, I get why Crowley calls you "Moose" now.

Castiel: These wounds have festered.
Meg: You really do know how to make a girl's nethers quiver, don't you?
Castiel: I am aware of how to do that. Although it doesn't usually involve cleaning wounds.
Meg: Why are you so sweet on me, Clarence?
Castiel: I don't know. And I still don't know who Clarence is.
Meg: Would it kill you to watch a movie, read a book?
Castiel: A movie, no. But a book with the proper spells... yeah, it could theoretically kill me.
Meg: You know, you're much cuter when you're shutting up.

Meg: So, your noodle's back in order?
Castiel: Yeah, my noodle remembers everything. I think it's a pretty good noodle.
Meg: Really? You remember everything?
Castiel: If you're referring to the pizza man... yes, I remember the pizza man. And it's a good memory.

Meg: I miss the simplicity. I was bad. You were good. Life was easier. now it's all so messy. I'm kind of good, which sucks. And you're kind of bad... which is actually all manner of hot. when We survive this... I'm gonna order some pizza and we're gonna move some furniture around. You understand?
Castiel: No, I--I... wait. Actually, I...
Dean: All right, let's roll, campers.

(after describing the last year of his happiness)
Meg: Hold on, there's one part I don't understand. You hit a dog and stopped. Why?
Sam: That whole story, and that's your takeaway?
Meg: Oh, I heard the rest. You fell in love with a unicorn. It was beautiful, then sad, then sadder. I laughed, I cried, I puked in my mouth a little.

Crowley: Castiel. So, that's who's been poking my boys... and not in a sexy way.

Crowley: I'm here for the stone with the funny scribbles on it.
Sam: That's not gonna happen.
Crowley: Love it when you get all tough. Touches me right where my bathing suit goes.

Crowley: Naomi. Fancy meeting you here. Haven't seen you in a dark age. Love the haircut.

Dean: Listen, I may not be able to carry the burden that comes along with these trials, but I can carry you.
Sam: You... realize you kind of just quoted Lord of the Rings, right?
Dean: Come on, man, but it's the Rudy hobbit. Rudy hobbit always gets a pass. Shut up.

Dean: Wait, are we talking a--a Maximum Overdrive situation here?

Maximum Overdrive is a 1986 movie written and directed by Stephen King, based on his short story "Trucks," which has machines coming to life and chewing up human beings.

Sam: And, by the way, since when does a demon possess someone then go all Beautiful Mind and--and start digging in the dirt?

A Beautiful Mind was a 2001 movie about mathematician John Forbes Nash Jr.

Sam: I'm Special Agent Lynne. This is my partner, Special Agent Tandy.

Richard Tandy and Jeff Lynne are band members with Electric Light Orchestra.

Meg: Aren't you a little short for a stormtrooper?

Leia says this to Luke when she first sees him (disguised as a stormtrooper) in Star Wars IV: A New Hope.

Meg: Every Crypt's been one Al Capone's vault after another.

In a April 1, 1986 two-hour syndicated TV special, Geraldo Rivera took a camera crew to Al Capone's vault in the Lexington Hotel in Chicago. It turned out there nothing of any value inside.

Dean: Cause I saw you Zero Dark Thirty that demon.

The 2012 movie Zero Dark Thirty generated controversy when showing that torture was successful in tracking down Obama bin Laden.

Dean: All right, Cass and I will head in and get our Indiana Jones on.

Indiana Jones is an iconic movie character, a two-fisted adventurer and archaeologist of the 1930s, 40s, and 50s, best known for his fedora, leather jacket, and bullwhip. The character appeared in four movies, a prequel television series, and numerous books.

Dean: Okay, bottom-line it for me, Bill Nye.

Bill Nye is the host of Bill Nye the Science Guy, a science show aimed at children.

Meg: Cut me, do I not bleed, Sam?

Shakespeare's The Merchant of Venice features a speech by Shylock where he notes, " If you prick us, do we not bleed? If you tickle us, do we not laugh? If you poison us, do we not die? And if you wrong us, shall we not revenge?"

Crowley: Timon and Pumbaa tell you their big plan?

In the Disney animated movie The Lion King (1994), Simba is taught how to eat bugs by Pumbaa and Timon.

Dean: Come on, man, but it's the Rudy hobbit.

Rudy is a 1993 sports movie about Daniel "Rudy" Ruettiger, who fought for his dream to play football for the University of Notre Dame. Sean Astin, who plays Rudy, also plays Sam in the Lord of the Rings trilogy.