Dean: You checked in two days ago under the name Richard Sambora. I think the scariest part about this whole thing is that you're a Bon Jovi fan.
Dean: This guy? (to Sam) You were drinking malt liquor?
Gas Station Clerk: Not after he whipped the bottle at my friggin' head!
Dean: This guy?
Gas Station Clerk: What, am I speaking Urdu?
Dean: What's going on with you, Sam? Hmmm? Cause smokin'... throwin' bottles at people... that sounds more like me than you.
Dean: You never told me this.
Sam: I didn’t want to scare you.
Dean: Well, bang up job on that.
(Dean's pointing a gun at Sam)
Dean: You know, I've tried so hard to keep you safe.
Sam: I know.
Dean: I can't. I'd rather die.
Dean: I'll call you later.
(as Dean leaves)
Jo: No, you won't.
Bobby Singer: Where’s Dean?
Sam: Holed up somewhere with a girl and a twelve-pack.
Bobby Singer: Yeah? Is she pretty?
Sam: You ask me, he’s in way over his head.
Sam: Dean, back from the dead. Getting to be a regular thing for you, isn't it? Like a cockroach.
Dean: How about I smack that smart ass right out of your mouth?
Sam: Oh, careful now. Wouldn't want to bruise this fine packaging.
Dean: Feel like talking now?
Sam: Sam's still my meat-puppet. I'll make him bite off his tongue.
Sam: You know when people wanna describe the worst possible thing? They say it's like Hell. Well, there's a reason for that. Hell is like, ah... well, it's like Hell. Even for demons. It's a prison made of bone, and flesh and blood and fear. And you sent me back there.
Sam: No. Not any more. Now I'm Sam. By the way, saw your dad there, he says "Howdy."
Sam: By the way, you really look like crap, Dean.
Dean: Yeah, right back at ya.
Bobby Singer: Here, take these.
Sam: What are they?
Bobby Singer: Charms. They'll fend off possession. That demon's still out there. This'll stop it from getting back up in ya.
Dean: That sounds vaguely dirty, but er, thanks.
Sam: No matter what I did, you wouldn’t shoot.
Dean: It was the right move, Sam, it wasn’t you.
Sam: Yeah, this time. What about next time?
Dean: Sam, when Dad told me I might have to kill you, it was only if I couldn’t save you. Now if it’s the last thing I do, I’m gonna save you.
Sam: Dean, what?
Dean: Dude, you like full-on had a girl inside you for a whole week. That's pretty naughty.
When Sam attacks Dean in the motel room, Dean lands and his right hand is out of shot. But in the next shot, his right hand is near his head, in the shot.
When the possessed Sam grabs Dean by his wounded shoulder, Dean reaches up and grabs Sam's right wrist. However, the camera then cuts to a rear shot and Dean's hand isn't at Sam's right wrist. In the next shot, Dean reaches up again
and grabs Sam's right wrist.
When Dean was shot, his jacket was on. However, in later scenes the jacket doesn't have any damage to it from the gunshot.