Dean: Hey, don't forget the extra onions this time, huh?
Sam: Dude, I'm the one who's gonna have to ride in the car with your extra onions.
Dean: Hey, see if they've got any pie. Bring me some pie! I love me some pie.
Andy Gallagher: I've been practicing, training my brain like meditation, right, so now it's not just thoughts I can beam out, but images, too, like anything I want. It's like bam, people they see it. This one guy I know, total dick. I use it on him... gay porn. All hours of the day. It's just like, you should see the look on his face. (everyone stares)
Ava Wilson: Sam, psychic abilities and spoon-bending... it's one thing. But demons?!?
Andy Gallagher: Sam... what are you doing here?
Sam: I don't know.
Andy Gallagher: What am I doing here?
Sam: I don't know, just...
Andy Gallagher: Where are we!?
Sam: Andy, look calm down.
Andy Gallagher: I can't calm down. I just woke up in friggin' frontierland!
Sam: What's the last thing you remember?
Andy Gallagher: Honestly... my fourth bong load.
Sam: Andy, you still with me, or what?
Andy Gallagher: Give me a minute, I'm still working through "Demons are real."
Sam: I think I know where we are now. Cold Oak, South Dakota, a town so haunted every single resident fled.
Ava Wilson: Swell. Good to know we're somewhere so historical.
Jake Talley: Salt is a weapon?
Sam: It's a brave new world.
Andy: (reading Dean's receipt) D. Hasselhoff?
Sam: Yeah. It's Dean's signature. It's kind of hard to explain.
Sam: I thought we were supposed to be...
Yellow-Eyed Demon: Soldiers, In a coming war? That's true. You are. But here's the thing. I don't need soldiers. I need "soldier." I just need the one.
Sam: What about my mom?
Yellow-Eyed Demon: That was bad luck
Sam: Bad luck?
Yellow-Eyed Demon: She walked in on us. Wrong place wrong time
Sam: What does that mean?
Yellow-Eyed Demon: It wasn’t about her, it was about you. It's always been about you.
Ava Wilson: I just stopped fighting it.
Sam: Fighting what?
Ava Wilson: Who we are, Sam.
Dean: (holding the dying Sam) Hey, hey... come here, come here, let me look at ya. Oh, hey look, its not even that bad.. It's not even that bad, alright? Sammy, Sam! Hey, listen to me, we are going to patch you up okay... You'll be as good as new. Huh? I'm going to take care of you, I'm going to take care of you! I gotcha. It's my job, right, watch after my pain-in-the-ass little brother.... Sam... Sam.... Sam! Sammy! (Sam dies) No.. no-n-n-n-n-no. Oh God. Oh God... Sam!
If it weren't for bad luck, we wouldn't have any luck at all.
Ava is quoting a line from the Albert King blues song "Born Under A Bad Sign". This song was also used as the name of an episode earlier in the season => "Born Under A Bad Sign
Andy: I just woke up in freakin' Frontierland.
Frontierland is one of the sections of Disneyland and Disney World. The rides, shows, and shops in this section of Disney is Wild West themed.
Sam: It's a brave new world.
Sam is quoting a line from Shakespeare's The Tempest. Brave New World is also the title of a novel by Aldous Huxley.