Teams leave Ecuador and fly to Santiago, Chile. Two teams snag an earlier flight, but they don't get the advantage they hoped to gain. Upon arrival in Santiago, the racers head to a copper-mining company for their next clue, a Roadblock. Each participant must search the board room for letters of the alphabet and unscramble them. Teams then fly to the city of Calama where they face a Detour. They can choose either By Hand, in which they must secure a tire to a truck, or By Machine, in which they must transfer gravel using a front loader. After completion, the racers drive to the Valley of the Dead to find the Pit Stop.