Sheldon decides to use his great mind to come up with the perfect prank to pull on Kripke after he was humiliated on National Radio because Kripke had put helium in Sheldon’s office (making his voice girly while on the radio). However, Sheldon uses many attempts, but can’t come up with a great scheme to pull back on Kripke, until a science experiment comes to his mind (which involves dropping lots and lots of foam from the ceiling right down on Kripke while recording the video to YouTube). Meanwhile, Howard is unsure if he wants to continue his relationship with Bernadette when he finds out she wants a commitment while he just wants sex.