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Season 4

37 :04x01 - Quality of Life

Apr/29/2013
Cathy plans Adam's sixteenth birthday party. Andrea struggles settling in with her new room-mate at fashion school. Paul brings in a new assistant.
Special Guest Stars: Phyllis Somerville as Marlene |
Guest Stars: Emma Noble as Amanda | Heather MacRae as Stephanie | Roslyn Ruff as Nurse | Connie Ray as Principal Connie Schuler | Kathy Najimy as Therapist | Alan Alda as Dr. Atticus Sherman | Samantha Futerman as Lydia Hye | Michael Ray Escamilla as Angel | Emily Tremaine as Dina | Liz Holtan as Amber | Brandon Tyler Harris as Ralph |
Uncredited: Booch O'connell as Restaurant Patron
Director: Michael Engler
Writer: Darlene Hunt

38 :04x02 - You Can't Take It With You

May/06/2013
Sean feels inspired to donate to charity. Cathy upsets Paul when she signs him up to an online dating service. Andrea struggles to impress her tutor, Isaac Mizhari.
Special Guest Stars: Isaac Mizrahi as Himself |
Guest Stars: Peter Bartlett as Himself | Brandon Williams as Himself | Jessica Dickey as Brenda | Jordan Simmons as Hostess | Bianca Amato as Susan Rand | Sujoy De as Store Worker | Wendy Rich Stetson as Waitress | Emily Tremaine as Dina | Jesse Newman as Hollis | Mary Joy as Marcy | Kathy Najimy as Therapist | Samantha Futerman as Lydia Hye | Neema Atri as Quirky Art Student |
Uncredited: Annika Merkel as Thrift Store Shopper
Director: Jann Turner

39 :04x03 - Quality of Death

May/13/2013
Dr. Sherman pays Cathy a visit who has checked herself into a hospice and is experiencing problems with her new room-mate. Adam confronts Paul about his lack of parental guidance. Andrea seeks inspiration from Cathy.
Special Guest Stars: Isaac Mizrahi as Himself |
Guest Stars: Les J.N. Mau as Hiro | Lee Aaron Rosen as Cop | Kyle Beltran as Jose | Emily Mechier as Young Nun | Angela Wyndham Lewis as Day Nurse | Darlene Hunt as Hospice Adminastrator | Alan Alda as Dr. Atticus Sherman | Tijuana Ricks as Day Nurse | Dana Ivey as Herself | Christian Massa as John | Kathy Najimy as Therapist | Liz Holtan as Amber | Jesse Newman as Hollis | Michael Ray Escamilla as Angel | Bianca Amato as Susan Rand | Tom Morrissey as Sid | Jennifer Mudge as Nurse Valerie |
Uncredited: Dennis Michael Giammetta as Fashion Spectator
Director: Richard Heus
Writer: Jenny Bicks

40 :04x04 - The Finale

May/20/2013
Adam surprises everyone when he fulfils one of Cathy's wishes. Cathy's estranged Dad visits her. Andrea gets the opportunity of a lifetime. Sean has mixed feelings about his impending kidney surgery.
Special Guest Stars: Isaac Mizrahi as Himself | Phyllis Somerville as Marlene |
Guest Stars: Marin Mazzie as Janelle Milson | David Andrew MacDonald as Ray Milson | David Wilson Barnes as Wesley | Marceline Hugot as Ina | Bianca Amato as Susan Rand | Connie Ray as Principal Connie Schuler | Brian Dennehy as Dad | Kathy Najimy as Therapist | Darlene Hunt as Hospice Adminastrator | Judy Gold as Rabbi | Ramsey Faragallah as Imam | David Aaron Baker as Priest | Michael Ray Escamilla as Angel | Jen Sese as Florist |
Uncredited: Rosemary Howard as Hospital Visitor
Director: Michael Engler
Warning: The Big C guide may contain spoilers
Classification: Scripted
Genre: Comedy | Family
Status: Ended
Network: SHOWTIME ( USA)
Airs: Mondays at 09:00 pm
Runtime: 30 Minutes
Premiere: August 16, 2010
Ended: May 20, 2013
This guide is currently edited by:
TomSouthwell (Challenge)

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