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| Season 16 | (Add Episode) |
Episode # ![]() |
Airdate | Title | Rating | |
| 1938 | 16x01 | 03/Jan/2011 | Paul Giamatti | 7 |
| 1939 | 16x02 | 04/Jan/2011 | Sen. Kirsten Gillibrand | 8 |
| 1940 | 16x03 | 05/Jan/2011 | Jimmy Wales | 8 |
| 1941 | 16x04 | 06/Jan/2011 | Patton Oswalt | 8 |
| 1942 | 16x05 | 10/Jan/2011 | Denis Leary | 6 |
| 1943 | 16x06 | 11/Jan/2011 | Colin Firth | 5 |
| 1944 | 16x07 | 12/Jan/2011 | Tim Pawlenty | 7 |
| 1945 | 16x08 | 13/Jan/2011 | Ron Howard | 8 |
| 1946 | 16x09 | 17/Jan/2011 | Peter Bergen | 7 |
| 1947 | 16x10 | 18/Jan/2011 | Neil deGrasse Tyson | 8 |
| 1948 | 16x11 | 19/Jan/2011 | Paul Clemens | 8 |
| 1949 | 16x12 | 20/Jan/2011 | Kambiz Hosseini & Saman Arbabi | 8 |
| 1950 | 16x13 | 24/Jan/2011 | Anand Giridharadas | 8 |
| 1951 | 16x14 | 25/Jan/2011 | James Franco | 7 |
| 1952 | 16x15 | 26/Jan/2011 | Jonathan Alter | N/A |
| 1953 | 16x16 | 27/Jan/2011 | T. Boone Pickens | 7 |
| 1954 | 16x17 | 31/Jan/2011 | Bill Gates | 8 |
| 1955 | 16x18 | 01/Feb/2011 | Michael Steele | 7 |
| 1956 | 16x19 | 02/Feb/2011 | Matthew Perry | 8 |
| 1957 | 16x20 | 03/Feb/2011 | Adm. Michael Mullen | 7 |
| 1958 | 16x21 | 14/Feb/2011 | Edward Glaeser | 6 |
| 1959 | 16x22 | 15/Feb/2011 | January Jones | 7.5 |
| 1960 | 16x23 | 16/Feb/2011 | Brian Williams | 8.5 |
| 1961 | 16x24 | 17/Feb/2011 | Ed Gillespie | 7 |
| 1962 | 16x25 | 21/Feb/2011 | Lisa Ling | 8.5 |
| 1963 | 16x26 | 22/Feb/2011 | Anderson Cooper | 9 |
| 1964 | 16x27 | 23/Feb/2011 | Donald Rumsfeld | 7.5 |
| 1965 | 16x28 | 24/Feb/2011 | Austan Goolsbee | 7 |
| 1966 | 16x29 | 28/Feb/2011 | Howard Stern | 7.5 |
| 1967 | 16x30 | 01/Mar/2011 | Prince Zeid Raad | 6 |
| 1968 | 16x31 | 02/Mar/2011 | Allison Stanger | 7.5 |
| 1969 | 16x32 | 03/Mar/2011 | Diane Ravitch | 9 |
| 1970 | 16x33 | 07/Mar/2011 | Sen. Rand Paul | 7.5 |
| 1971 | 16x34 | 08/Mar/2011 | Brian Christian | 7.5 |
| 1972 | 16x35 | 09/Mar/2011 | Aaron Eckhart | 6.5 |
| 1973 | 16x36 | 10/Mar/2011 | Trey Parker & Matt Stone | 9.5 |
| 1974 | 16x37 | 21/Mar/2011 | Sarah Vowell | 9 |
| 1975 | 16x38 | 22/Mar/2011 | T.J. English | 7 |
| 1976 | 16x39 | 23/Mar/2011 | Richard Lewis | 6.5 |
| 1977 | 16x40 | 24/Mar/2011 | Bret Baier | 9 |
| 1978 | 16x41 | 28/Mar/2011 | Dr. Mansour O. El-Kikhia | 6.5 |
| 1979 | 16x42 | 29/Mar/2011 | Miguel Nicolelis | 7 |
| 1980 | 16x43 | 30/Mar/2011 | Jake Gyllenhaal | 8 |
| 1981 | 16x44 | 31/Mar/2011 | Norm MacDonald | 7 |
| 1982 | 16x45 | 04/Apr/2011 | Billy Crystal | 8 |
| 1983 | 16x46 | 05/Apr/2011 | Colin Quinn | 7 |
| 1984 | 16x47 | 06/Apr/2011 | Mike Huckabee | 7 |
| 1985 | 16x48 | 07/Apr/2011 | Jamie Oliver | 9 |
| 1986 | 16x49 | 11/Apr/2011 | Foo Fighters | 7 |
| 1987 | 16x50 | 12/Apr/2011 | Gov. Deval Patrick | 9 |
| 1988 | 16x51 | 13/Apr/2011 | Tracy Morgan | 8 |
| 1989 | 16x52 | 14/Apr/2011 | Ricky Gervais | 7 |
| 1990 | 16x53 | 25/Apr/2011 | Gigi Ibrahim | 7 |
| 1991 | 16x54 | 26/Apr/2011 | Elizabeth Warren | 9 |
| 1992 | 16x55 | 27/Apr/2011 | Sen. Bernie Sanders | 9 |
| 1993 | 16x56 | 28/Apr/2011 | William Cohan | 7 |
| 1994 | 16x57 | 02/May/2011 | Philip K. Howard | 7 |
| 1995 | 16x58 | 03/May/2011 | Rachel Maddow | 7 |
| 1996 | 16x59 | 04/May/2011 | David Barton | 8 |
| 1997 | 16x60 | 05/May/2011 | Jon Meacham | 7 |
| 1998 | 16x61 | 09/May/2011 | Keira Knightley | 7 |
| 1999 | 16x62 | 10/May/2011 | Will Ferrell | 8 |
| 2000 | 16x63 | 11/May/2011 | Albert Brooks | 8 |
| 2001 | 16x64 | 12/May/2011 | Kristen Wiig | 7 |
| 2002 | 16x65 | 16/May/2011 | Jon Ronson | 8 |
| 2003 | 16x66 | 17/May/2011 | Annie Jacobsen | 8 |
| 2004 | 16x67 | 18/May/2011 | Richard Beeman | 9 |
| 2005 | 16x68 | 19/May/2011 | Lisa P. Jackson | 7 |
| 2006 | 16x69 | 31/May/2011 | Jimmy Fallon | 8 |
| 2007 | 16x70 | 01/Jun/2011 | Bill Moyers | 7 |
| 2008 | 16x71 | 02/Jun/2011 | Tim Tebow | 8 |
| 2009 | 16x72 | 06/Jun/2011 | Maziar Bahari | 7 |
| 2010 | 16x73 | 07/Jun/2011 | Fareed Zakaria | 7 |
| 2011 | 16x74 | 08/Jun/2011 | Larry King | 7 |
| 2012 | 16x75 | 09/Jun/2011 | Howard Wasdin | 7 |
| 2013 | 16x76 | 13/Jun/2011 | Alex Prud'Homme | 7 |
| 2014 | 16x77 | 14/Jun/2011 | J.J. Abrams | 8 |
| 2015 | 16x78 | 15/Jun/2011 | Trey Parker & Matt Stone | N/A |
| 2016 | 16x79 | 20/Jun/2011 | Ray Nagin | 8 |
| 2017 | 16x80 | 21/Jun/2011 | Cameron Diaz | 6 |
| 2018 | 16x81 | 22/Jun/2011 | Mitchell Zuckoff | 9 |
| 2019 | 16x82 | 23/Jun/2011 | Bruce Headlam | 7 |
| 2020 | 16x83 | 27/Jun/2011 | Jennifer Aniston | 10 |
| 2021 | 16x84 | 28/Jun/2011 | Louis C.K. | 8 |
| 2022 | 16x85 | 29/Jun/2011 | Tom Hanks | 8 |
| 2023 | 16x86 | 30/Jun/2011 | Bill Kristol | 7 |
| 2024 | 16x87 | 11/Jul/2011 | Denis Leary | 7 |
| 2025 | 16x88 | 12/Jul/2011 | Kid Rock | 8 |
| 2026 | 16x89 | 13/Jul/2011 | Matthew Richardson | 7 |
| 2027 | 16x90 | 14/Jul/2011 | Sgt. 1st Class Leroy Petry | 9 |
| 2028 | 16x91 | 18/Jul/2011 | Daniel Radcliffe | 8 |
| 2029 | 16x92 | 19/Jul/2011 | Pervez Musharraf | 7 |
| 2030 | 16x93 | 20/Jul/2011 | Steve Carell | 8 |
| 2031 | 16x94 | 21/Jul/2011 | Scott Miller | 8 |
| 2032 | 16x95 | 25/Jul/2011 | Neil Patrick Harris | 7 |
| 2033 | 16x96 | 26/Jul/2011 | Juan Williams | 9 |
| 2034 | 16x97 | 27/Jul/2011 | Rachel Weisz | 9 |
| 2035 | 16x98 | 28/Jul/2011 | Peter Tomsen | 8 |
| 2036 | 16x99 | 01/Aug/2011 | Freida Pinto | 8 |
| 2037 | 16x100 | 02/Aug/2011 | Jason Bateman | 7 |
| 2038 | 16x101 | 03/Aug/2011 | Austan Goolsbee | 8 |
| 2039 | 16x102 | 04/Aug/2011 | Sen. Dick Durbin | 8 |
| 2040 | 16x103 | 08/Aug/2011 | Mark Adams | 8 |
| 2041 | 16x104 | 09/Aug/2011 | Jay Bahadur | 7 |
| 2042 | 16x105 | 10/Aug/2011 | John Coffee | 9 |
| 2043 | 16x106 | 11/Aug/2011 | Michael Wallis | 9 |
| 2044 | 16x107 | 15/Aug/2011 | Ali Velshi | 8 |
| 2045 | 16x108 | 16/Aug/2011 | Matt Long | 7 |
| 2046 | 16x109 | 17/Aug/2011 | Michael Steele | 7 |
| 2047 | 16x110 | 18/Aug/2011 | Anne Hathaway | 10 |
| 2048 | 16x111 | 06/Sep/2011 | Buddy Roemer | 8 |
| 2049 | 16x112 | 07/Sep/2011 | Dr. Sanjay Gupta | 8 |
| 2050 | 16x113 | 08/Sep/2011 | Marion Cotillard | 9 |
| 2051 | 16x114 | 12/Sep/2011 | Adm. Mike Mullen | 8 |
| 2052 | 16x115 | 13/Sep/2011 | Jim Lehrer | 10 |
| 2053 | 16x116 | 14/Sep/2011 | Common | 8 |
| 2054 | 16x117 | 15/Sep/2011 | Caroline Kennedy | 8 |
| 2055 | 16x118 | 20/Sep/2011 | Ron Suskind | 8 |
| 2056 | 16x119 | 21/Sep/2011 | Gov. Mitch Daniels | 7 |
| 2057 | 16x120 | 22/Sep/2011 | Jennifer Granholm | 10 |
| 2058 | 16x121 | 26/Sep/2011 | Rep. Ron Paul | 8 |
| 2059 | 16x122 | 27/Sep/2011 | Seth Rogen | 8 |
| 2060 | 16x123 | 28/Sep/2011 | Bill O'Reilly | 8 |
| 2061 | 16x124 | 29/Sep/2011 | Tony Bennett | 8 |
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