After being shot during a police chase, Kimble takes refuge at a Navajo reservation school in Arizona. Once there, he's befriended by a teacher who removes the bullet but a persistent deputy sheriff is slowly closing in pursuit.
Kimble is the only man who can clear a police officer accused of wrongfully killing a youthful robber but can he do it without his identity being revealed?
Kimble tracks the one-armed man to a seemingly peaceful suburban town that's actually controlled by a gambling syndicate. Not wanting any rocking the boat of his operation, the syndicate boss orders both men out of his town--immediately.
Working as a janitor in an apartment building, Kimble becomes the leading suspect when a woman is bludgeoned to death.
Back in Stafford, the ever persistent Lt. Gerard gets the local newspaper to put up a reward of ten grand for information leading to Kimble's re-capture. This complicates things for Kimble in his newest identity as he's already involved with an autistic girl as well as an escaped killer.
Kimble clashes with a Christian Scientist whose religion forbids the use of antibiotics to help his ailing grandson.
After spotting Fred Johnson's picture in a photograph, Kimble tracks down the one-armed man through the photographer who snapped the photo. The two men scuffle in a chemical plant where Johnson is working. An explosion results which leaves Kimble blinded.
During a labor strike at a winery, Kimble witnesses the son of the winery owner kill a union leader.
Kimble gets involved with a woman and her mentally handicapped brother.
After helping an injured galpal of the one-armed man, Kimble must avoid a trap set at a hospital by Lt. Gerard.
Kimble gets involved in a labor dispute between father and son fishermen.
On the run with the authorities in hot pursuit, Kimble's only avenue of escape is to throw in with a gang of outlaw motorcyclists.
Kimble and an immigrant Hungarian family are taken hostage by an escaped killer.
After Kimble saves his life, a former mobster is determined to repay the debt by killing Lt. Gerard.
Kimble is held hostage at a mountain cabin by three men determined to find out the location of missing stolen loot taken by an accomplice whom Kimble was forced to bring to the cabin.
For the umpteenth time, Kimble gets involved in a father-son conflict. This time it's a small-town sheriff who's son was wounded while attempting a robbery.
A government agent, in pursuit of a fugitive embezzler, also happens upon Kimble, who's working as a deck hand on the embezzler's boat.
A dying building contractor demands that Kimble use his medical skills long enough to keep him alive to finish his latest project.
Hot on the trail of the one-armed man, Kimble meets up once again with Sister Veronica, a nun whom he had encountered two years earlier in Angels Travel Lonely Roads.
Attending a minor league baseball game, Kimble witnesses the kidnapping of a newspaper publisher's daughter.
The one-armed man, now working as a handyman on a college campus, is recognized by an academic friend of Kimble's who tries an experiment to get him to confess.
A man plots to murder his invalid wife and pin the crime on the nearest patsy--Kimble.
An Afro-American deputy is assigned to escort two captured prisoners to jail in Helena, Montana. One is a vicious racist and the other is Dr. Richard Kimble.
Working in a cigar store, Kimble is once again caught up in a father-son conflict and must rely on the son to help him escape from the police.
Recognized by a research doctor in Mexico, Kimble is blackmailed into helping with the man's nefarious experiments.
Cornered in Washington D.C., Kimble is given temporary asylum inside the embassy of an African nation.
Kimble, working as a truck driver, becomes involved romantically with the company's radio dispatcher and soon discovers that she's a convict on a work release program. The you know what hits the fan when her parole officer recognizes Kimble.
Fleeing from a sheriff's deputy into the Oregon hills, Kimble meets up with an ailing eccentric whose only companions are two vicious dogs.
Working as a truck driver in Tucson, Kimble receives word that the one-armed man is being held in a Los Angeles jail so he heads for Tinsel Town. Unfortunately for the fugitive physician, Lt. Gerard is there as well and he sets a trap which Kimble is unable to elude.
Kimble faces the end when he is re-captured by Gerard in Los Angeles and taken back to Stafford. But unknown to both men, the one-armed Fred Johnson has also arrived in Stafford and he proceeds to blackmail a prominent citizen of the town who knows what really happened on the night Helen Kimble was murdered.