When the girls thwart Mojo Jojo's attempt to steal Chemical X, he invents an evil video game to control their minds and bodies.
Curses: The Powerpuff Girls start saying bad words after they hear the Professor say a couple of them.
Bang For You Buck: When the Powerpuff Girls and the Gangreen Gang find a destructo ray in Mojo Jojo's garage sale, they try to earn the most money so they can buy the ray first.
Silent Treatment: The Professor takes the Powerpuff Girls to a silent movie to teach them that silent movies are better than movies today, but the Powerpuff Girls get bored quickly and are forced to go inside the movie to save the Professor.
Sweet N' Sour: A group of cute little animals, who are criminals, are robbing Townsville blind. These criminals have an advantage because of their cute looks. It's up the Powerpuff Girls to stop them, but how?
Prime Apes: Back when Mojo tried use primates to try to take over the world, there was Mopey Popo, who didn't didn't get his due. But now he's back and wants to be evil!
Coup D'Ete: The Professor is trying out his new car, but the car is taking him away from the Powerpuff Girls.
Make Zen To Me: After reading a fortune cookie, Buttercup goes on a journey to find inner peace.
Say Uncle: The Professor at first tells the Powerpuff Girls all about Eugene, his younger brother and how he was so wild back in the day and when Eugene is coming to Townsville, the Powerpuff Girls mistake him for a monkey.
Guest Stars: Keone Young
as Monk, Server | Elizabeth Daily
as Woman #1, Dude #2 | Tom Kenny
as Chap #2, Chubby Guard, Man, Dude #1 | Tom Kane
as Snooty Man | Jim Cummings
as Doctor, Fuzzy Lumpkins | Jennifer Hale
as Mary | Dee Bradley Baker
as Chap #1, Messenger, Scrawny Guard, Beastman, Eugene | Tara Strong
as Julie Bean, Mother, Baby | Catherine Cavadini
as Woman #2
Reeking Havoc: The Professor wants to win the 2nd Townsville Annual Cook-Off and the Powerpuff Girls help by putting chemical X in the chili to make it special. The Professor wins but the chili has a surprise on the people of Townsville.
Live and Let Dynamo: In this episode, Dynamo returns but is now destroying Townsville. Who is controlling Dynamo?
Guest Stars: Tom Kenny
as Peace Man, Guy, Man #2, Snake, Lil' Arturo | Tom Kane
as Construction Guy, Crowd Member #5 | Roger L. Jackson
as Butch, Crowd Member #7 | Rob Paulsen
as Homie #2 | Jennifer Martin
as Ms. Bellum | Jeff Bennett
as Homie #1 | Kevin Michael Richardson
as Gas Monster, Man #1, Washer, Dog, Man #3 | Catherine Cavadini
Oops, I Did It Again: The Professor tries to do something on purpose because his experiments that were successful were just accidents.
Mo' Linguish: As part of his community service, Mojo Jojo begins teaching English at the Learning Annex. Soon, everyone starts to talk like Mojo!
Guest Stars: Tom Kenny
as Jimmy, Arturo, Enrique | Tom Kane
as Judge, Vendor | James Arnold Taylor
as Fella, Man, Phillipe, Cop | Roger L. Jackson
as Ernst, Robber, Ming | Jennifer Hale
as Lady, Nadia | Jeff Bennett
as Ace, Grubber, Harouk | Jennifer Martin
as Ms. Bellum | Elizabeth Daily
as Betty | Tara Strong
There's a new villain named Mask Scara who is defacing all of the posters of Townsville. Mask Scara gives people horrible makeovers that are almost impossible to take off. Now the Professor must find the cure for these makeovers and also Blossom must stop Mask Scara.
Little Miss Interprets: The Powerpuff Girls think that the Professor is making new little girls when they hear the Professor trying to make something out of sugar, spice and everything nice.
Night Mayor: The Powerpuff Girls go into the Mayor's dreams when he keeps having the same dream over and over again but never sees the end.
Custody Battle: The Rowdyruff Boys are back on Father's Day and Mojo Jojo discovers that Him is their father and made them much better than Mojo did. So, Him and Mojo go in a competition to see who is the better dad.
The City Of Nutsville: Bubbles is not allowed to talk for a week when she gets stung in the mouth by a bee.
The Gangreen Gang is committing crimes that are brilliant. They have to steal magical items for Sedusa so she can get revenge on the Powerpuff Girls for cutting her hair.
That's Not My Baby! : The Powerpuff Girls try to look for a baby's mother, but they couldn't find her. They decide to care for the baby themselves and prove to the Professor that they can own a hamster.
Simian Says: Mojo Jojo kidnaps the Narrator and decides to take over as narrator and control the Powerpuff Girls' actions.
Sun Scream: The Powerpuff Girls' super powers are weakened because they got sun-burned.
The City Of Frownsville: Everyone is happy when a carnival arrives in Townsville, but Lou Gubrious, a man who keeps shedding tears, sets out a crying ray on Townsville. Now the town will be flooded, unless someone saves the day.
Professor Utomium sends little girls with super powers called the Steamypuff Girls (who look a lot like the Powerpuff Girls) to save the western version of Townsville from Mojo the Kid.
Crazy Mixed Up Puffs: The Powerpuff Girls literally as one must stop Mojo Jojo from destroying Townsville.
Mizzen In Action: Captain Crack McGraigen and his crew go forward in time to the present. They find chemical X and now they have super powers.
What's The Big Idea: The Powerpuff Girls try to stop Mojo from taking over Townville.
Roughing It Up: The Professor and the Powerpuff Girls go on an old-fashioned vacation to the Townsville Swamp, but the trouble is that Fuzzy Lumpkins and his nephews are at the Townsville Swamp too.
In exchange for the Powerpuff Girls' powers, a gnome will offer world peace.