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In this year's exceptionally evil Halloween episode, Marge accidentally murders Ned Flanders and is haunted by his ghost in "I Know What You Diddily-Iddily Did", Bart and Lisa become superheroes who must rescue Xena's Lucy Lawless from The Comic Book Guy in "Desperately Xeeking Xena", and Homer causes an computer-generated apocalypse in "Life's a Glitch, and Then You Die".
voiced Homer Simpson, Abraham Simpson, Krusty the Klown, Barney, Willy, Sideshow Mel, Mayor Quimby, Hans Moleman, Gil, Itchy, Various
voiced Marjorie "Marge" Bouvier Simpson, Patty Bouvier, Selma Bouvier, Jacqueline Ingrid Bouvier, Various
voiced Bart Simpson, Nelson Muntz, Ralph Wiggum, Todd Flanders, Kearney, Various
voiced Apu, Moe, Chief Wiggum, Carl, Comic Book Guy, Dr. Nick Riviera, Prof. Frink, Cletus, Sea Captain, Kirk Van Houten, Various
voiced Mr. Burns, Smithers, Dr. Marvin Monroe, Ned Flanders, Seymour Skinner, Otto, Kent Brockman, Dr. Hibbert, Lenny, Rev. Lovejoy, Various
Couch: After watching Kang and Kodos's lame Halloween special, the family members (mostly) appear as characters in previous Halloween episodes: Homer is a jack-in-the-box (from "Treehouse of Horror II"), Bart is a mutant fly (from "Treehouse of Horror VIII"), Marge is a witch (also from "Treehouse of Horror VIII"), and Maggie is an alien (from last season's "Treehouse of Horror" ["Treehouse of Horror IX"]); Lisa, an ax murder victim (the only one not based on a previous episode), asks what aliens have to do with Halloween. Maggie yells, "Silence!" in a deep voice before disintegrating Lisa with a ray gun.
This would be the last Treehouse of Horror to air during the holiday season instead of after until season 21's Treehouse of Horror.
Lisa: Look at the wonders of modern technology now.
Homer: Wonders, Lisa, or blunders?
Lisa: I think that was implied by what i just said.
Homer: Implied or implode?
Lisa: Mom, make him stop!
(as the second-rate celebrities sing)
Bart: Don't worry, Dad. We'll be dead in five minutes.
Homer: NOT FAST ENOUGH!
(Homer pushes the eject button on their seats. The seats take off out of the rocket and they float through the atmosphere. Because of the vacuum of space, their heads grow big and explode.)
Mysterious Voice: I know you're alone!
Homer: Uh... who is this?
Mysterious Voice: Is this... Maude Flanders?
Homer: No it's Homer...
Moe: Oh! Hey Homer, it's Moe! I must have dialed the wrong number.
Homer: Hey….we just got away with murder! And it was so easy (sees Milhouse in street) you know… I've never liked that little wiener Milhouse (turns to run over, Marge stops him)
Marge: No more murders!
Homer: But you got to kill…
The first segment of this episode, titled "I Know What You Diddily-Iddily Did", is in reference to the 1997 movie "I Know What You Did Last Summer".
The title "Life's a Glitch, Then You Die" of the final segment of this episode, is in reference to the line "life's a bitch, then you die", from the 1951 movie "When Worlds Collide".