Series creator Matt Groening guest stars as himself and is called the creator of Futurama for obvious reasons.

Chalkboard: None

Couch: Repeat of the couch gag from "The Regina Monologues" where The Simpsons are formed from a Play-Doh Fun Factory press.

"Edna K." Song Lyrics:
(To the tune of "The Lion Sleeps Tonight")
Castrati: Oh Edna K.
Oh Edna K.
Oh Edna K.
Oh Edna K.
Oh Edna K.
Oh Edna K.
Oh Edna K.
Oh Edna K.
Skinner: Miss Krabappel
A sad principal is desperate and needy
If you come home I won't die alone and that's what I'd prefer
Bart: Oh pleeeeeeease settle for Seymour
So pleeeeeeease come back to the dork!

Edna: I'm not marrying you, either!
CBG: There are a million valid reasons, but which one did you pick?
Edna: We've had a great time together but we're too different.
CBG: I don't understand.
Edna: It's like I'm DC Comics and you're Marvel.
CBG: I understand completely.

Klingon Priest: (Klingon line)
Marge: I do.
Homer: Marge, you just agreed to raise the kids Klingon!
Marge: D'Oh!

This episode's title is an adaptation of “My Big Fat Greek Wedding”, a 2002 Canadian and American romantic comedy film written by and starring Nia Vardalos, John Corbett and directed by Joel Zwick.