In the opening sequence, Bart is writing "The pilgrims were not illegal aliens" on the board.
Couch: A pair of cartoon hands opens up a book called "The Simpsons" and reveals a pop-up centerfold of the family sitting on the couch.
Bart: You should stop being so mean to us kids.
Comic Book Guy: Well, I suppose you could buy some comics at the dry cleaners.
(Comic Book Guy has just noticed a new comic store that has opened up across the street.)
Comic Book Guy: Philip K Dick! It can't be! It's as if Superman moved to Gotham City!
Martin: Which he did, in World's Finest Comics #94. (Points to the comic.) See?
Comic Book Guy: That was an imaginary story, dreamt by Jimmy Olsen after he was kicked in the head by Supergirl’s horse, Comet. It never really happened.
Bart: None of these things ever really happened.
Comic Book Guy: Get out of my store.
Comic Book Guy: Nice work, Doctor Boo-Who. Your tears have smudged Wolverine's iconic sideburns. Hence, you must buy this comic. And the cost of your innocnet accident is... 25 dollars, please.
Milhouse: But that's the money Yaya Sophia gave me for Greek Orthodox Easter.
Comic Book Guy: (Sighs) I hate when they tell me things about themselves.
Lisa: I really identified with the girls in Ghost World. They made me feel like I wasn't so alone.
Dan Clowes: Yeah, yeah, whatever. Do you know anyone at Batman? 'Cause I really want to draw Batman, I'm awesome at utility belts. (points to a picture of a utility belt.)
Dan Clowes: Check these out. This is where the Batman keeps his money in case he has to take the bus.
There is a reference to OK Go's music video of Here it Goes Again.
This episode's title is a probable reference to 'Husbands & Wives', the 1992 Woody Allen movie.