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Team Venture find themselves in the middle of the Bermuda Triangle were Dr. Venture searches for a long lost experimental spaceship that his father, Dr. Jonas Venture, designed and tested their. it crashed somewhere along the Bermuda Triangle and was lost at sea, until now. But the spirit of it's pilot, Major Tom, and a ship full of "Ghost Pirates", whom intend to take over Dr. Venture's ship, might make retrieving the experiments space craft more difficult then it already is.
The opening flashback's dialogue, where Major Tom takes Venture's spacecraft for a test flight, is taken almost entirely from two David Bowie songs, "Space Oddity" and "Ashes To Ashes".