Elizabeth Woodville, a widowed commoner, waits by the roadside with her two young sons. Her husband has been killed fighting for deposed Lancastrian King Henry VI and her wealth has been confiscated. Her only hope is to try to catch the eye of her family’s greatest enemy, York King Edward IV. It works, and the king stops and visits her family home at Grafton.
Elizabeth’s coronation ends up being a very grand affair. She and her mother Jacquetta then get to work, marrying off her siblings to the nobility to make sure of their family’s security, and create a royal family loyal to Edward as he attempts to bring peace to England. The Lancastrians are stripped of their titles and Margaret Beaufort is determined to do something about it.
In an effort to further her son's claim to the throne, Margaret joins Warwick's rebellion against Edward. The rebellion fails though and the traitors are forced to flee for their lives. Jasper Tudor goes into exile, while Warwick and George make their way to France. Elizabeth and Jacquetta turn to witchcraft to try and stop them.
Elizabeth feels troubled after hearing the news of Isabel and George’s dead son. Rumours begin to surface that Warwick is making a new alliance with his old enemy, Margaret of Anjou and planning to restore her husband Henry VI to the throne. George is not happy as it means that he will now never be King. Elizabeth and Jacquetta visit George’s mother, Cecily, and point out that her son could now be fighting for Lancaster and at risk of being executed.
Warwick is dubious of George's loyalty so sends Isabel back to England to keep him on side. Anne is forced to trust old enemies. Edward secretly visits Elizabeth.
Elizabeth is facing a difficult future as all she holds close everything that is threatened. She is expecting once again but feels unease about Edward’s closeness to his brothers.
Elizabeth loses a child after giving birth and after he is handed to Margaret Beaufort he comes alive in her hands and Elizabeth thinks that Margaret has saved him. Anne also gives birth to a baby boy, and is living happily away from court. After she realises though that her husband Richard Duke of Gloucester has brought her mother to live with them, her piece is shattered. Edward IV is determined to wage war with France.
Elizabeth is worried that Edward is allowing Henry Tudor to return back home from exile. Edward reveals to her that he would rather have his enemies close. After Edward suddenly becomes extremely ill he names his brother Richard as Lord Protector on his deathbed. Elizabeth is devastated following his death as she is no longer Queen and her fortunes have gone.
Worried about his enemies, King Richard III honours Brackenbury, Buckingham and Stanley. Still not convinced that Elizabeth’s threat is over, Anne secretly talks to Brackenbury behind her husband’s back, wanting the Princes in the Tower dead.
Queen Anne Neville’s health is beginning to fade fast and after her son Prince Edward passes away and she hears of her husband’s love for Princess Elizabeth, she knows that she is ready to die.