An image of Anna, the V's leader, is projected worldwide and asks the world to join together with the Vs. Meanwhile, Chad gets an exclusive interview with Chad, and Tyler sees the Vs as being his ticket to being a part of something big.
Erica and Father Jack find themselves being tracked by a "Seeker" from the V's. Meanwhile, Chad, thinking his last interview with Anna didn't go so well, tries to be more investigative on his next newscast.
Chad reports inside the Peace Ambassador Center as 100 visas are issued to the first group of American Visitors. Meanwhile, Erica beings to track a death threat while paired with a V officer, and Ryan tries to build up more opposition to the V's.
Erica works with the allies to uncover a biological threat they believe the V's have been plotting. On the Mothership, Anna meets with a special guest, and Chad does a segment on V Healing Centers, but is conflicted by his findings.
Erica finds her life in danger when she's attacked at home; a dangerous new member is recruited for the Resistance, as the Visitors shore up their defenses; Anna wonders why Chad hasn't followed up on his diagnosed aneurysm; and Ryan's concern grows over Val's "abnormal" pregnancy.
Anna introduces her program to invite select humans to stay on the 29 spaceships; Ryan must deal with Valerie's pregnancy being wildly accelerated; Tyler learns a secret about his mother.
Erica, Ryan and Jack go on a harrowing mission to find the legendary John May in order to rescue Georgie, Anna brings Chad aboard the Mothership for a story on her Live Aboard Program, and Tyler confronts his mom about his mysterious past.
Chad and Anna are in Geneva, Switzerland for the U.N. Energy Summit, where Anna is going to present a gift of technology to the world.
Meanwhile, Erica learns that the V Task Force is investigating The Fifth Column, and Valerie goes on the run, knowing something is different about her baby and not sure she can trust Ryan.
Erica, Father Jack and Hobbes realize that the Vs know names and addresses of The Fifth Column members and must take drastic measures to protect them. Meanwhile, Ryan finally reveals to Val that he's a Visitor, and Chad, with the camera rolling for "Prime Focus," begins the process aboard the Mothership's Medical Bay to have his aneurysm removed.
Ryan, Erica, Father Jack and Hobbes try to avoid being caught by a deadly V tracker team; Chad confronts Father Jack.
After a violent attack on someone very close to Anna, she delivers a message that the Vs don’t feel safe and will be leaving; and Anna also gives a list of possible Fifth Column members to Chad, hoping he’ll investigate to help in finding them. Meanwhile, Erica and the team try to track down a scientist who may have created a weapon that the Visitors are afraid of
The episode opens with the V soldier still on the hunt for Val, while for her part, Val's water breaks and her baby with Ryan will soon be born. Meanwhile Erica, tired of being on the defensive, decides to go on the offensive and gets herself and Tyler invited up to the Mothership for a get-to-know-everyone-better dinner. But she has more than food on her mind; she's really there to find Anna's soldiers and destroy them. And Chad, after Father Jack asks him to help get a message on the ship to Joshua, discovers the awful truth that Anna's been using him.
The Season Two opener, "Red Rain," continues the action from last season's finale when Anna unleashed Red Sky on the planet. With the world on the brink of war and chaos all around, is there anyone who can stand up to Anna? Meanwhile, Ryan has been kept in isolation on the mothership, away from his hybrid baby so that Anna can experiment on her; Chad, seeking redemption for being used by Anna, now wants to fight with the Fifth Column; and Erica goes on a journey to find a scientist who can give her the answers to what Red Sky is, and where she learns the horrifying secret of what the V's are doing on our planet
Anna and Diana square off in the dark bowels of the Mothership - Diana has been down there for 15 years and not had a single glimpse of Anna.
Meanwhile, Erica has Tyler's blood analyzed, and learns the V's did something sinister to her when she was pregnant with him.
Erica learns her partner, Malik, is a Visitor and must fight for her life - literally - to stop Anna from finding out she's Fifth Column.
Meanwhile, Anna learns that Malik is missing and orders Ryan to find her, while Lisa realizes her body is beginning to change, causing her to become more and more like her mother.
After the radical faction of the Fifth Column murders three Peace Ambassadors, Erica goes on a mission to hunt down their leader, Eli Cohn, a former Mossad agent. Meanwhile, as Jack and other priests around the globe begin to speak out against the Visitors, Anna heads to the Vatican in an effort to convince the leaders of organized religion that the Visitors truly are "of peace".
Anna uses her newest gift to mankind, "Concordia," as a cover to hide an invading fleet of breeding vessels that will be used to ensure the perpetuation of Visitors for future generations. Meanwhile, Eli Cohn tries to convince Erica and the Fifth Column that the "Concordia" gala is the perfect time to assassinate Anna.
Anna, enraged at the increasing audacity of the Fifth Column attacks, enlists Ryan in an attempt to wipe out the Fifth Column in one fell swoop. Meanwhile, Father Travis, following Vatican orders, asks Jack to leave the church, and Lisa meets Diana, her grandmother -- who Anna said was dead -- for the first time.
Erica, seeking revenge against Anna, heads to Hong Kong to carry out a mission to strike a lethal blow against Anna. Meanwhile, Anna learns that Tyler's phosphorous level is too low - even after the Red Rain -- and he might become useless to her; and Lisa and Diana bond, beginning to form an alliance against Anna.
Erica, now officially in charge of the global Fifth Column, leads them in a high risk attack against Anna. Anna meanwhile, growing closer in her plan to destroy humanity, finds a major obstacle in a certain Live Aboard candidate; and Ryan sneaks back onto the Mothership to try and rescue his daughter.
Anna is about to pull the switch on the planet's first Blue Energy reactor, but Sid realizes that the size of the reactor is much too large for just the various Concordia sites - the Fifth Column needs to figure out what Anna is really up to. And Diana tells Lisa she must act against Anna now, fulfill her destiny and save humans from annihilation.
Anna is focused on having Lisa breed with Tyler to ensure the evolution of the Visitors, while Erica and Diana enlist Lisa to stage a coup against Anna and remove her from power before humanity is destroyed. Erica and the Fifth Column join Lisa in the attempted coup, which has devastating results.