The gift's that Bo was born with have never been easy to understand; now aged 10 her powers are getting stronger still and much more dangerous. Tate, a wrongfully imprisoned prisoner who's serving time on death row, has lost all will to carry on until he's tasked with protecting Bo.
On the run toward Philadelphia, Tate decides to use Bo's talents to make some money at a casino. Meanwhile, Skouras uses his political connections to enlist the aid of the FBI, but not before hiring a backup tracker of his own.
Bo and Tate arrive in Manhattan, unaware that the FBI net is closing in on them. Bo takes the time to help a wealthy woman who is still mourning the loss of her son after decades.
Winter desperately looks for a way off Manhattan island for Bo and Tate while Bo has her own agenda, helping a couple find each other. Skouras prepares his own agent to find Bo.
Someone in Skouras' organization is leaking information to a blogger, which draws Bo and Tate to help them. The culmination of events leads to a confrontation between Bo and Joshua.
After being released from his ankle bracelet, Tate returns home to find answers why he ended up in prison for murder. After Joshua's defeat, Skouras looks for another telepath to turn into a weapon for the military.
An encounter with one of Skouras' teams leaves Bo in a coma, and forces Winter to take drastic action to save her life. Flashbacks reveal Channing's surprising history with Bo.
Learning that Skouras perfected the machine that can track telekinetics, Winter goes on the offensive. Meanwhile, despite warnings, Bo is compelled to help a man who is at the end of his rope.
While Winter relocates his organization, Tate oversees Bo's exercises until she has a vision of a disaster that she desperately wants to stop. Meanwhile, Skouras finds another strong telepath for Orchestra's purposes.
When Bo has a premonition of a tragic event in the New York City subway, she convinces Tate to help her in stopping her vision from becoming reality. A confrontation with FBI Agent Ferrell in the subway station quickly changes course when an explosion leaves them trapped underground. Meanwhile, Dani proves herself to Skouras as she settles into her new home at Orchestra.
As Channing struggles to recover from her gunshot wound, Winter takes desperate measures to keep her alive. With Winter distracted, Bo and Tate sneak away to confront Skouras and demand he stop pursuing them. Meanwhile, Dani begins to question her position at Orchestra.
When an enraged Dani concentrates her powers on the destruction of Orchestra and Bo, Skouras turns to Winter and Channing for help. Bo and Tate's attempt to start fresh on their own is short-lived when Bo has intense visions of Dani, and pulls them back into danger.
Bo uses her powers to help a struggling police officer.