Cannon, a crusty retired baseball champ and hero of Dr Howard Sheinfeld's childhood days, puts Sheinfeld's ethics to the test when he pleads to have his life ended because of a terminal disease.
Dr. Sheinfeld is shocked when his estranged son unexpectedly appears at the hospital sporting a New Wave look and accompanied by a buddy who is under the influence of drugs.
There's more madcap happenings in the emergency room when a doctor who retired 10 years ago reports to work. There's also a patient with a hole in his head, who cannot remember how it got there.
Dr. Howard Sheinfeld faces fatherhood and divorce for a second time, while Dr Eve Sheridan has something to hide.
Dr Sheinfeld may have found a way out of his financial problems — giving up his job at the hospital in favour of a more profitable position in genetic research. However, he is undecided as he feels sentimental attachment to his "overworked, underpaid" job at the emergency unit.
An explosive and dangerous situation arises in the hospital's emergency room involving the entire medical staff.
Meanwhile, Dr Sheinfeld good-humouredly auctions off his private practice.