(The guys try to figure out how to help Jim keep track of his medication) Steve: Alright, I am going to write down every time you take something. Jeff: This is good. This is going to work. I can call this my Heath Ledger.
Jim's play off of the name "Heath Ledger" is funny because the actor, Heath Ledger, died from drug use.
When Jim's awkwardness with Katie comes from having been caught kissing her by her husband in the previous episode, 'Sober'.