At Hula School the students are hearing about a certain quiz show called Ohana-Rama Lilo and Mertle challenge each other to the show so Lilo goes to the quiz show with her family Mertle does the same and who will win Mertle or Lilo?
Lilo is happy that she may have found a friend that doesn’t think she’s weird, though Mertle attempts to tell her new friend just the opposite. In hopes of ensuring her new friend likes her, Lilo decides to hold a ‘Lilo Isn’t Weird Party’, though when an experiment causes Lilo and Stitch to switch minds, the two must try to act like the other in hopes of getting the party to work without any problems.
Lilo wants to grow up, and fast. She thinks she has her wish when she finds an experiment that can do it. But be careful what you wish for, for the future is bleak.
Dr. Drakken is hired by Hamsterveil to capture Stitch, underwater. So Pleakley logs onto Kim Possible's website. Lilo wants to help, even though Kim treats her like a kid.
Jumba mistakes Rufus as an experiment.
On the aniversery of her parents death, an experiment gets caught in Lilo's dreams and turns them into nightmares. Its up to Jumba, Pleakley and Stitch to retreve it before its too late.
Mrs Hasagawa's Cats: Lilo and Stitch try to help Mrs. Hasagawa around her shop and house, but don't do so well. They discover that she's housing multiple experiments.
Ace: The Evil Genius organization (EGO) decide to see how evil Jumba is, inorder to see if Jumba's fit to stay in the club, while an experiment with no evil intentions is activated.
Glitch: Jumba fully automates the house when an experiment that causes electronics to malfunction gets inside it.
Woops: When an activated, clumsy experiment almost blows Hamsterveil's secret lab, he sends all his experiments to Gantu.
After Nosy tells Lilo and Stitch that the rest of experiments are on Gantu's ship, they plot a recon mission. Meanwhile, Gantu and 625 tricks Angel into singing her siren song, and plan to use it to revert the experiments living on the island.
An experiment called Link tries to bring together people who won't cooperate.