While on a train to El Paso to deliver a lecture at a conference, Jessica crosses paths with a woman who eventually disappears under mysterious circumstances. As she starts to investigate, Jessica soon discovers that the woman was in government protection after witnessing a whistle-blower get murdered to keep quiet about a top secret satellite code that has several fatal flaws in it and may have her own secrets to keep.
In the days following a party attended by numerous museum board members, Jessica gets involved with an investigation of several home invasion robberies that are connected to a highly sought after hairstylist that is rumored to leaving a popular beauty salon to start his own salon chain. When a scheming entrepreneur is found dead in the hairstylist’s chair, the Lieutenant in charge of the investigation suspects that the salon owner is the one who committed the murder, Jessica soon uncovers some clues that promptly make her suspect the victim’s wife and mistress are the ones who committed the crime.
As Laney Boswell is taking a walk with her friend and lawyer Terry Folger, she gets news that her husband died after losing control of his car and drove off a cliff. In the month since his death, Jessica arrives in Aspen to visit Laney and soon discovers that her friend is the prime suspect in her husband’s death and that a witness can prove that Laney was seen purchasing various tools to tamper with her husband’s car. Following the death of the witness, Jessica and Private Investigator Charlie Garrett team up with the local sheriff who is in charge of the investigation to prove Laney’s innocence and that her husband is actually alive and trying to commit insurance fraud.
After deciding to visit a friend in Gila Junction, Arizona, Jessica reluctantly gets involved with several investigations, one of which surrounds the death of a resident that recently found a large cache of money believed to have been stolen by an area truck-stop bandit and hid in the desert.
While in New Orleans to research a new novel, Jessica gets involved in an investigation of a series of murders that are the cause of voodoo curses. Following the death of a friend’s husband, Jessica soon discovers that his death seems to be apart of the other murders, especially when a voodoo doll is found at the scene of the crime. As she investigates his death, Jessica discovers that while the housekeeper and her daughter may have motives for wanting him dead, the man’s business associates got to him before the women could hurt him.
Jessica is in for an eerie trip to Ireland to visit a friend, when a young woman, who disappeared the previous year, is found dead in a dungeon not long before her arrival. After checking into her friend’s inn, Jessica soon discovers that an American businessman is trying to buy the inn in an attempt to turn it into first-class Americanized hotel. Thrown into the mix is another friend of Jessica’s, this one an inspector who is working undercover at the inn, possible illegal sales of priceless Irish artifacts, and the death of a hotel worker causes Jessica to stare death in the face when she gets locked in the same dungeon that Nan was found in.
As Rory and Eileen work to free Jessica from the dungeon, Eileen’s son Ian tries to secure funding to save his mother’s inn. Upon being saved, Jessica is able to convince her friends and the authorities that Nan was murdered and that her death has to do with covering up an intricate smuggling ring of Irish artifacts.
After the federal government probes the disappearance of several board members of a stock brokerage house, Jessica gets subpoenaed as a hostile witness when it is discovered that she spoke to a witness who was eventually murdered.
After discovering that a rising Latin band is involved with the head of a shady recording company, Jessica works on getting an A&R from a big company to distribute their debut album. But when a petty thug who works for the shady recording company is murdered, Jessica has to work with the cops to find out what the motive was and who was behind his death.
When Jessica arrives in Cabot Cove to go to a benefit concert, she gets caught up in a murder investigation when the headliner is electrocuted during a sound check.
While working with a young editor on her new book, Jessica learns that she just read a manuscript by another author recounts with pinpoint accuracy of her kidnapping that happened years ago. When it looks like the authorities are reluctant to believe the girl’s story, Jessica offers to help her gain closure in what happened and is surprised at what she finds in their investigation.
When a puppet that Jessica created is adapted for television show, she arrives on the set to see her creation come to life. However, when several individuals have different ideas for the puppet and blackmail abounds as a result, Jessica has to solve a murder that occurred at the studio.
While visiting the lodge in the Grand Tetons, Jessica soon learns that the owner; an old friend and retired Colonel who is planning on running for public office, is being blackmailed to into calling off his bid for office. Things get sticker for him when a murder takes place and he is the prime suspect. It is up to Jessica and the man’s family to prove his innocence in the murder and in the past event that took place when he was still in the Army that he is being blackmailed for.
Following the death of a prominent businessman, Deputy Andy is accused of planting evidence against a shoe manufacturer he bought a house with numerous problems from. When the manufacturer ends up dead one night, Andy becomes the prime suspect in his murder. As a result, Jessica goes to work on clearing the deputy’s name.
Upon her arrival in Atlanta for an Amateur Mystery Writers convention, Jessica gets involved with a FBI investigation when a lethal virus is stolen from a Biological Research Institute. Following the death of her friend Mark, Jessica starts an investigation of her own to discover the identity of his murderer and why they wanted him dead.