Oxygen is available to view on cable and satellite across the United States and was launched in 1998. It is available in 70 million homes and targets the younger female audience. It is part of Oxygen Media. The network originally was geared towards broadcasting interactive programs with a black bar across the bottom containing a variety of information. Later, the black bar was removed and the programming included reruns and first run reality shows and movies.

The network makes a variety of different shows including Oprah After the Show, The Janice Dickinson Modeling Agency and Campus Ladies.