Klugman’s wife Peggy said the actor was home in Northridge when he passed, while speaking to KABC- TV in Los Angeles earlier today.
On “The Odd Couple,” Klugman played sloppy sportswriter Oscar Madison to Tony Randall’s neat photographer Felix Unger. The show was executive produced by Garry Marshall and was based on a Neil Simon play. The two men were best friends in real life, and Randall died at age 84 back in 2004.
Klugman then played a medical examiner on NBC’s “Quincy M.E.” Klugman also starred in a short- lived sitcom called “You Again?” with a young John Stamos playing his son.
Klugman also appeared on Rod Sterling’s “The Twilight Zone” four times.
"You made my whole family laugh together," wrote Jon Favreau on Twitter.
He lost his voice due to throat cancer in the ‘80s and trained himself to talk again.
Klugman, whose wife was at his side when he died, is also survived by his sons David and Adam and two grandchildren.
No more details were available at this writing.