At Evergreen Academy, only three boys are enrolled: Jed, Phil and Cary. For the boys, their typical days are filled with awkward moments and sexist remarks directed at them. Cary is a ladies' man, but can't manage to charm Stella, an outspoken feminist who wants nothing to do with him. Jed is interested in Miranda, who already has a boyfriend, and has to chose between going after Miranda, or being with Kate, a girl who likes him. Phil, being the smartest of the three, is always dreaming up plans, but they never work.
Opposite Sex ran 6 of the 8 episodes; it was canceled by FOX in August of 2000.
While Jed is dating Miranda and Kate, he eventually breaks up with Miranda, who then wants revenge resulting in Kate breaking up with Jed. Phil then tries to make his move on Kate, but in the end, everyone ends up in the hospital.