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  Season 1 (Episode Guide) Season 2 »
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 Season 1(Add Episode)
Episode #  Airdate Title Rating
1 1x01 25/Nov/2005 Mandy Moore N/A
2 1x02 05/Dec/2005 Keira Knightley N/A
3 1x03 06/Dec/2005 Elle MacPherson N/A
4 1x04 08/Dec/2005 Wynonna Judd N/A
5 1x05 09/Dec/2005 Amanda Bynes N/A
6 1x06 12/Dec/2005 Lee Ann Womack N/A
7 1x07 13/Dec/2005 The Sopranos' Steve Schirripa N/A
8 1x08 14/Dec/2005 Jon Favreau N/A
9 1x09 15/Dec/2005 Rob and Amber from Survivor N/A
10 1x10 16/Dec/2005 Carla Gugino & Elisabeth Hasselbeck N/A
11 1x11 19/Dec/2005 Tom Arnold N/A
12 1x12 20/Dec/2005 Shania Twain N/A
13 1x13 21/Dec/2005 Niecy Nash N/A
14 1x14 22/Dec/2005 Andie MacDowell N/A
15 1x15 23/Dec/2005 Sarah Jessica Parker N/A
16 1x16 26/Dec/2005 Rachael Ray N/A
17 1x17 27/Dec/2005 Selma Blair N/A
18 1x18 28/Dec/2005 Matthew Modine N/A
19 1x19 29/Dec/2005 Rent's Anthony Rapp N/A
20 1x20 30/Dec/2005 Gastineau Girls N/A
21 1x21 01/Jan/2006 Isaac Makes You Fashion Fabulous N/A
22 1x22 02/Jan/2006 Madonna N/A
23 1x23 03/Jan/2006 Finola Hughes N/A
24 1x24 08/Jan/2006 Isaac and the City N/A
25 1x25 09/Jan/2006 Sela Ward N/A
26 1x26 13/Jan/2006 Andrew Firestone N/A
27 1x27 18/Jan/2006 Rob Morrow N/A
28 1x28 20/Jan/2006 Cynthia Nixon N/A
29 1x29 23/Jan/2006 Nia Long N/A
30 1x30 27/Jan/2006 Bo Bice & Shannon Elizabeth N/A
31 1x31 30/Jan/2006 Margaret Cho N/A
32 1x32 03/Feb/2006 Michael Moloney N/A
33 1x33 10/Feb/2006 Kimora Lee Simmons N/A
34 1x34 11/Feb/2006 Isaac's Glamour Girls N/A
35 1x35 13/Feb/2006 Iman N/A
36 1x36 19/Feb/2006 Isaac Strikes Again N/A
37 1x37 21/Feb/2006 Rosie Perez N/A
38 1x38 24/Feb/2006 Lisa Loeb N/A
39 1x39 27/Feb/2006 S. Epatha Merkerson & J.C. Chasez N/A
40 1x40 03/Mar/2006 Gabrielle Union N/A
41 1x41 04/Mar/2006 Isaac's It Girls N/A
42 1x42 06/Mar/2006 Jamie Lynn Sigler N/A
43 1x43 10/Mar/2006 Gina Gershon N/A
44 1x44 13/Mar/2006 Huey Lewis N/A
45 1x45 16/Mar/2006 Tony Danza N/A
46 1x46 18/Mar/2006 Isaac's Famous Friends N/A
47 1x47 06/Apr/2006 Isaac's TV Darlings N/A
48 1x48 14/Apr/2006 Isaac's Celebrity Field Trips N/A
49 1x49 12/May/2006 Keira Knightley N/A
50 1x50 13/May/2006 Selma Blair N/A
51 1x51 14/May/2006 Niecy Nash N/A
52 1x52 15/May/2006 Finola Hughes N/A
53 1x53 16/May/2006 Madonna N/A
54 1x54 19/May/2006 Gastineau Girls N/A
55 1x55 22/May/2006 Lisa Loeb N/A
56 1x56 25/May/2006 Jamie Lynn Sigler N/A

    Season 2 »
Warning: Isaac guide may contain spoilers
Classification: Talk Shows
Genre: Celebrities | Fashion/Make-up | Interview
Status: Canceled/Ended
Network: Esquire NETWORK ( USA)
Airs: Mondays, Tuesdays, Wednesdays, Thursdays, Fridays
Runtime: 60 Minutes
Premiere: December 05, 2005
Ended: May 25, 2007
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