The Hopkins doctors are baffled when a school teacher brings in a young girl she adopted from China who had a mysterious prior heart surgery and is now needing a leak repaired. Dr. Alfredo Quinones does a brain operation on a patient who is wide awake. ER doctor Anne Czarnik gives stitches to a fellow doctor who gets flirtatious with her and asks her to leave no scars. After witnessing a young child go into cardiac arrest, surgical intern Oscar Serrano feels the pressure from his chosen profession. Dr. Andy Cameron wants to be a transplant surgeon and must face the fact that his father is a living legend in the field.