The first show starts out with a group of young interns getting some of the finer points of what's in store for them from Dr. Goodwin (Peppard). A young idealistic intern (Christian Raines), challenged a highly-reputed veteran of the operating room, Dr. Wilson, when he loses a patient through ineptness. The story seems to stick to the formula as Wilson's report is accepted in the hospital's Morbidity-Mortality Conference and the intern's residency is cancelled.
However, the chief of neurosurgery and star of the show (George Peppard as Dr. Jake Goodwin) persists in his investigations of the incident.
A sub-plot about a child who has mysteriously suffered an apparent stroke turns out to be a warning for parents rather than simply an overblown device to gain our sympathy and to give an intern self-confidence..