Q & Q is about two friends Aristides Quarles van Ispen and Wilbur Quant. Both in the first and in the second series they on track of some criminals. Because they are halfly believed by the adults, they go out on research, thereby helped by Aristides' great-uncle: 'grandpa' Reinier Quarles van Ispen. In the second series they are assisted by their friend Akkie Swaan. In the first series the adventure starts when the boys want photograph birds. At developing the photo's it seems they have accidentally photographed a dead man. This detail has been borrowed from the film Blow-up
of Michelangelo Antonioni
. The beginning up to the second series is a telephone conversation that accidentally is eavesdropped on by Wilbur .