An explosion goes off making everyone worried it is a bomb. Ethel Bennett and Dr Millais Culpin attempt to help the angry victims. Sister Russell clashes with Mr Dean.
Nurse Goodley believes that surgeon Henry Dean is ignoring the side-effects caused by a new anesthetic. Nurse Bennett worries that her relationship with Dr Culpin has been discovered after Matron Luckes decides to send her into private nursing.
Sister Ada Russell's health suffers as she works too hard. Nurse Goodley finds herself drawn to Saul Landau on the ward but Saul has a illness which is life threatening.
Sister Russell catches Nellie Bowers on her way out to meet a mysterious young man. Dr Henry Head decides to try out an experiment on himself.
After Ethel Bennett takes to her dying brother in a naval hospital, Dr Culpin finds himself powerless to help. Mr Dean's cocaine addiction looks like it will ruin his career. Sister Russell attempts to help a young mother breaking Matron's rules along the way.
Matron Luckes clashes with Sister Russell after she finds out that she she helped a family living in the slums. Dr Culpin isn't happy that Bennett has stopped studying to become a doctor. The team have to deal with the victims of a sweatshop fire.