Present: After spending years apart, Mary Elizabeth Simms, a homemaker in Birmingham and Rene Jackson, a prominent lawyer in Washington. D.C. get reacquainted after Rene's father passes away.
Past: Mary Elizabeth and Rene form a friendship after stealing a pack of cigarettes.
Present: Rene represents a woman when her rapist sues her for custody of a child conceived during the rape. M.E. has to deal with Kelly and her failing grades.
Past: As M.E. spends time with Rene and her family, she begins to learn more about blacks. This results in her confronting her families major racism with much backlash in return.
Present: A mean-spirited neighbor sues M.E., who turns for help to Rene in a property-damage case that escalates into a nasty wrangle over the Sims' dog.
Past: M.E. and Rene worry about the Cuban Missile Crisis.
Present: M.E. and Colliar are closing in on their 26th wedding anniversary. Colliar has big plans for the day, but not everything goes as planned.
Past: M.E. gets into a fight with Tully. Later, M.E. and Colliar have their first kiss.
Present: Rene plans a ceremony for her father's honor and asks M.E. to write a biography for the event. However, in doing research for the biography, M.E. uncovers some shocking information.
Past: As "Project C" is happening in Birmingham, Rene and M.E. team up to help the Jackson family get ready for it.
Present: A family friend asks Rene to defend him on corruption charges. After some convincing, Rene ultimately agrees, despite M.E. being horrified that Rene would represent such a person.
Past: The Jacksons prepare for the Birmingham March and Rene gives them her St. Christopher medal for good luck.
Present: M.E. punishes Kelly for three weeks after finding a beer bottle in the family living room, despite Kelly telling her that the bottle isn't hers. Meanwhile, Rene represents a woman whose son was threatened at school.
Past: Teresa catches M.E. and Rene spying on her.
Present: Mary Elizabeth tries to find help for her family. Rene represents a boy whose family cut him out of the inheritance due to his spiritual beliefs.
Past: Grandma Otis gives M.E. advice on how to have a loving heart.
Present: Rene represents the parents of a child who passed away due to being infected with AIDS.
Past: Rene decides to pursue law after seeing her father in court.
Present: Rene is hired to represent a white couple who were barred from adopting a black foster daughter. Meanwhile, M.E. suffers an ectopic pregnancy.
Past: Johnny is grounded after he, M.E. and Rene participate in a protest after they are refused service at a drive-in diner.
Present: Rene is hired as a lawyer for a lesbian couple who cannot get married on public property.
Past: Rene and M.E. are taught the birds and the bees.
Present: Rene is hired to defend a black family that was evicted from their property, resulting in reviewing Alabama laws that outlaw interracial marriages.
Past: Rene takes care of her father and brother for a weekend; M.E.'s parents worry that she is focusing too much on a man.
Present: A stalker enters Rene's life; Teresa visits Colliar, but things do not go well.
Past: Colliar and Rene dislike M.E.'s recent bossy attitude; Rene is refused treatment at an all-white hospital.
Present: Rene has to go to lengths to deal with her stalker.
Past: Rene and M.E. sneak out to go to a carnival.
Present: Rene's cousin from which she has been estranged for 20 years comes for a visit.
Past: Rene looks up to her aunt, a singer in the choir.
Present: Rene takes on the case of a white man who was beaten up by police.
Past: Rene has her first real date.
Present: Rene is shocked to learn that Bill is not divorced, but only separated from his wife.
Past: M.E. and Rene watch Martin Luther King, Jr.'s march on Washington, including his infamous "I Have A Dream" speech.
Present: A childhood friend offends Rene and M.E. after they pull a prank at a parade.
Past: Rene has her first crush; M.E. breaks Colliar's leg by accident
Present: Rene mails M.E.'s stories to a publisher in New York, jump starting her writing career.
Past: Rene and M.E. have to spend time apart when M.E. goes to Texas to visit family.
Present: Mary Elizabeth and Colliar are shocked when Davis is suspended from school due to "sexual misconduct."
Past: M.E. and Rene try to be a part of a "boys only" tree house club.
Present: Mary Elizabeth and Rene head to Los Angeles to visit Teresa.
Past: M.E. and Rene decide to run away; Matt and James must find them.
Present: Mary Elizabeth helps Rene get ready to meet Billy's children.
Past: M.E. and Rene try to come up with a way to make enough money to buy some sea monkeys.
Rene represents a man who has been ordered to be sterilized despite not wanting to do so. Meanwhile, young Rene and M.E. go to a segregated concert.
As Rene and Bill go house hunting, a new intern bonds with M.E.'s boss. Meanwhile, the new girl at school has her eye on young Colliar.
M.E.'s daughter decides to go gothic while Rene is sued for malpractice. Meanwhile, young Rene baptizes M.E.
Bill's children begin to cause everyone stress. At work, M.E. is pressured to lie for a co-worker. Meanwhile, young Rene and M.E. go door-to-door selling Girl Scout cookies in an all-white neighborhood.
Rene decides to take her first defense case in which she must defend a black man who is accused of the murder of a white man 35 years ago. Meanwhile, M.E. is not happy that her son has joined the football team and even less thrilled at how his teammates treat him. In the past, young Rene and M.E. are shocked to find a strange woman living in Port Dixie.
Rene and Bill debate whether or not to elope. In the past, M.E.'s uncle threatens young Rene's family.
Rene is hired to defend a reckless driver. In the past, young M.E. makes a new friend.
Rene's estranged brother arrives in town. In the past, young Rene and M.E. play with fireworks.
M.E. and Rene talk about modern day racism. Meanwhile, M.E.'s uncle threatens young Rene's father.
M.E. and Rene talk about modern day racism. Meanwhile, M.E.'s uncle threatens young Rene's father.
Rene represents a witness to a murder. M.E. and Colliar must deal with money problems. Meanwhile, young Rene and M.E. get word of the Holocaust.
M.E. and Colliar's relationship is put to the test as the anniversary of their son's death nears. Meanwhile, young M.E. and Colliar have their first kiss.
M.E. trains for her new job; young Rene supports a black man who sat at the front of a bus.
M.E. and Colliar go on a date; young M.E. and Rene bury a doll.
Colliar and Davis go hunting; Rene defends a teacher accused of being a witch; young M.E. and Rene deal with becoming women.
Rene's college friend arrives in town, and her presence creates friction between Rene and M.E. Meanwhile, young Rene and M.E. see Mary Poppins.
M.E. decides to make a will; Rene begins dating a white man; and young M.E. and young Rene learn of a shocking incident.
Rene is hired to defend a teen in a malpractice suit. Young Rene and M.E. give Tully's cousin a makeover.
M.E. must deal with a burglary. Young Rene and M.E. start to gamble.
M.E. begins to suspect that her neighbor is a pedophile. Meanwhile, young Rene and M.E. visit a haunted house.
Rene represents Bill in a case. Meanwhile, young M.E. worries that Colliar may be cheating.
Rene and M.E. go to their high school reunion.
Rene represents a child in a murder case. Meanwhile, young Rene and M.E. get their first taste of alcohol.
In the present day, Rene must face police discrimination. In the past, young Rene and M.E. begin to see changes in their older brothers.
Rene decides to become a part of the "Big Sisters" organization. Meanwhile, young M.E. wants Rene to take advantage of Theresa.
Everyone is shocked when an Asian-American man claims to be Johnny's son. Meanwhile, young M.E.'s brother leaves for Vietnam.
Rene must decide whether or not to make April undergo a drug test.
Rene is involved in a case involving reverse discrimination. Meanwhile, the FBI begins to watch James.
M.E. begins to write a book about the civil rights movement. Young Rene's mother comes out as a civil rights leader following James' arrest.
M.E. and Colliar begin to think Kelly and her new boyfriend are moving too quickly in their relationship. Meanwhile, young Rene falls for a white boy.
Rene faces getting in trouble at work when she agrees to represent an illegal alien. Meanwhile, young M.E. delivers an ultimatum to Colliar.
Kelly learns she is pregnant. Meanwhile, young Rene and M.E. deal with their respective boyfriend issues.
Rene isn't sure what to think when her campaign manager hires an image consultant. Meanwhile, young M.E. learns the process Rene must go through to relax her hair.
During her candidacy, Rene admits to using drugs. Meanwhile, young M.E. and Rene protest the demolition of Port Dixie.
Even after heart surgery, Rene's focus remains on her career rather than her health. As M.E. urges her best friend to take better care of herself, Davis makes plans for his future by applying to a Catholic preparatory seminary against his parents wishes.
Rene begins feeling uneasy about Turk because their relationship is heating up. Plus her first day back at work after her surgery proves to be a tough one as one client begins to get under her skin.
Rene resumes her full-time schedule and represents an artist who paints pictures of U.S. currency, while M.E. serves on a jury in which she finds herself in lone dissent in the case.
M.E. ponders becoming involved in a class action lawsuit that has been filed against a comedy club because of fat joke told during one stand-up's performance; Rene decides to confirm her commitment to Turk.
Rene is welcomed into Turk's family with a hideous heirloom engagement ring; M.E. continues to encourage Kelly and Adjani to settle their differences once and for all.
In the series finale, Rene's wedding falls on the same day that she is set to argue in favor of reparations for slavery. Meanwhile, M.E. is offered a teaching job.
In the past, the girls protest beauty-queen standards.