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Season 1

1 :01x01 - : Kirstie Alley

Actress Kirstie Alley and Dr. Ian Smith discuss weight loss; Fran's parents drop by.
Interviewees: Kirstie Alley as Herself

2 :01x02 - Season 1, Episode 2

Actor Dan Aykroyd; actress Donna Dixon; the secret to finding success.
Guest Stars: Dan Aykroyd as Himself | Donna Dixon as Herself

3 :01x03 - Turning Pain Into Purpose

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Guest Stars: Rosie O'Donnell as Herself

4 :01x04 - Celebrating differences

Comic Margaret Cho; director Rob Reiner; a panel discussion on bullying; actor Jai Rodriguez.
Guest Stars: Margaret Cho as Herself | Rob Reiner as Himself | Jai Rodriguez as Himself

5 :01x05 - overcoming adversity

Actor William Shatner; entrepreneur Kelly Fitzpatrick; Dr. Aymee Coget; Peter Frampton performs.
Guest Stars: William Shatner as Himself | Peter Frampton (1) as Himself

6 :01x06 - Season 1, Episode 6

Actress Eva La Rue; lawyer Gloria Allred; stylist Brenda Cooper; rock stars' jewelry; the Living Sisters perform.
Guest Stars: Eva La Rue as Herself | Gloria Allred as Herself

7 :01x07 - Season 1, Episode 7

Minnie Driver and Liz Phair perform; actress Marlo Thomas; Ethan Bortnick performs; documentary filmmaker Laurie David.
Guest Stars: Minnie Driver as Herself | Liz Phair as Herself | Marlo Thomas as Herself | Ethan Bortnick as Himself | Laurie David as Herself

8 :01x08 - Season 1, Episode 8

Actor Tony Danza; designer Eduardo Xol; chef Fabio Viviani; animal trainer Dave Salmoni brings a kinkajou and a baby leopard.
Guest Stars: Tony Danza as Himself

9 :01x09 - Season 1, Episode 9

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Guest Stars: Lauren Lane as Herself

10 :01x10 - Season 1, Episode 10

Actors Renée Taylor, Ann Morgan Guilbert, Mario López, Boris Kodjoe and Nicole Ari Parker; Tichina Arnold performs.
Guest Stars: Renée Taylor as Herself | Ann Morgan Guilbert as Herself | Mario López as Himself | Boris Kodjoe as Himself | Nicole Ari Parker as Herself |
Musical Guests: Tichina Arnold as Herself

11 :01x11 - Season 1, Episode 11

Talk-show host Larry King; reality star Kim Zolciak; actor Gilles Marini; actor Daniel Davis.
Guest Stars: Larry King as Himself | Kim Zolciak as Herself | Gilles G. Marini as Himself (as Gilles Marini) | Daniel Davis as Himself

12 :01x12 - Season 1, Episode 12

Wayne Brady performs; throwing a holiday party.
Guest Stars: Wayne Brady as Himself | Charles Shaughnessy as Himself
Warning: The Fran Drescher Tawk Show guide may contain spoilers
Classification: Talk Shows
Genre: Interview
Status: Canceled/Ended
Network: FOX ( USA)
Airs: Mondays, Tuesdays, Wednesdays, Thursdays, Fridays
Runtime: 60 Minutes
Premiere: November 26, 2010
Ended: December 17, 2010
Episode Order: 14
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