| Name (UnSort) | Character (Sort) | |
| •Alan Oppenheimer | voiced | Various |
| •Cam Clarke | voiced | Ooze, Various |
| •Clyde Kusatsu | voiced | Various |
| •David Ackroyd | voiced | Various |
| •David Coburn | voiced | Captain Planet |
| •David Warner (1) | voiced | Zarm (S04) |
| •Dean Stockwell | voiced | Duke Nukem (S01-S02) |
| •Ed Gilbert | voiced | Looten Plunder |
| •Edward Asner | voiced | Hoggish Greedly (S01-S06) |
| •Frank Welker | voiced | Suchi |
| •James Coburn | voiced | Looten Plunder (1990-1993) |
| •Janice Kawaye | voiced | Gi |
| •Jeff Goldblum | voiced | Verminous Skumm (1990) |
| •Jim Cummings | voiced | Sly Sludge (S04-S05) |
| •Joey Dedio | voiced | Wheeler |
| •Kath Soucie | voiced | Linka |
| •LeVar Burton | voiced | Kwame |
| •Lewis Arquette | voiced | Various |
| •Lou Rawls | voiced | Dr. Rice |
| •Margot Kidder | voiced | Gaia (S04-S06) |
| •Martin Sheen | voiced | Sly Sludge (1990-1993) |
| •Maurice LaMarche | voiced | Duke Nukem, Verminous Skumm (S03-S06) |
| •Meg Ryan | voiced | Dr. Blight (S01-S02) |
| •Patrick Pinney | voiced | Various |
| •Scott Menville | voiced | Ma-Ti |
| •Sting | voiced | Zarm (S01-S02) |
| •Theresa Saldana | voiced | Mame Slaughter |
| •Tim Curry | voiced | Mal |
| •Townsend Coleman | voiced | Various |
| •Whoopi Goldberg | voiced | Gaia (S01-S03) |