Velasquez, the first champion out of the American Kickboxing Academy, has been sidelined for more than a year with a shoulder injury ever since dethroning Brock Lesnar last October. He's finally rehabbed, healthy and ready for the big time.
Meanwhile, dos Santos is finally getting his big moment to shine. He's more than paid his dues with two victories in number one contender fights, as well as a season coaching The Ultimate Fighter (TUF) against Lesnar, but if he can knockout Velasquez and become the UFC heavyweight champion, it will be totally worth it.
Evans has been set back by repeated bad luck, missing out on a title shot in 2011 due to injury, and time and time again having his title shot delayed by injuries to Jon Jones or himself. He's already had two post-fight staredowns with Jon Jones and he'll be looking to earn his third with a victory over Phil Davis on Saturday night.
Phil Davis has been talked about as one of the last potential challengers to Jon Jones in the light heavyweight division. The former national champion wrestler out of Penn State holds a spotless record in MMA and has manhandled nearly every UFC opponent he's faced. He'll be hoping to do the same in what is clearly his toughest test to date.
Anthony Ferguson vs Michael Johnson (lightweight)
John Dodson vs Tim Elliott (flyweight)
Pascal Krauss vs John Hathaway (welterweight)
Danny Castillo vs John Cholish (lightweight)
Dennis Bermudez vs Pablo Garza (featherweight)
Louis Gaudinot vs John Lineker (flyweight)
Scheduled: Demetrious Johnson vs. John Dodson in a flyweight bout in Chicago. Also: Quinton "Rampage" Jackson vs. Glover Teixeira in a light-heavyweight contest.
Scheduled: Ben Henderson vs. Gilbert Melendez in a lightweight bout in San Jose. Also: Daniel Cormier vs. Frank Mir in a heavyweight contest.
Scheduled: Demetrious Johnson vs. John Moraga in a flyweight bout in Seattle.